Epanorin, a lichen secondary metabolite, inhibits proliferation of MCF-7 breast cancer cells

Epanorin, a lichen secondary metabolite, inhibits proliferation of MCF-7 breast cancer cells

Show other versions (1)

[Background] Epanorin (EP) is a secondary metabolite of the Acarospora lichenic species. EP has been found in lichenic extracts with antimicrobial activity, and UV-absorption properties have been described for closely related molecules; however, its antiproliferative activity in cancer cells has not yet been explored. It has been hypothesized that EP inhibits cancer cell growth. MCF-7 breast cancer cells, normal fibroblasts, and the non-transformed HEK-293 cell line were exposed to increasing concentrations of EP, and proliferation was assessed by the sulforhodamine-B assay.

Saved in:
Bibliographic Details
Main Authors: Palacios-Moreno, Juan, Rubio, Cecilia, Quilhot, Wanda, Cavieres, M. F, Peña de Torres, Eduardo de la, Quiñones, Natalia V., Díaz, Hugo, Carrión, Flavio, Henríquez-Roldán, Carlos F., Weinstein-Oppenheimer, Caroline R.
Other Authors: Comisión Nacional de Investigación Científica y Tecnológica (Chile)
Format: artículo biblioteca
Language:English
Published: BioMed Central 2019-10-10
Subjects:Epanorin, Cancer, Cytotoxicity, Mutagenesis, Cell cycle, Apoptosis,
Online Access:http://hdl.handle.net/10261/192581
http://dx.doi.org/10.13039/501100002848
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

http://hdl.handle.net/10261/192581
http://dx.doi.org/10.13039/501100002848

Similar Items