Porcine intramuscular fat content and composition are regulated by quantitative trait loci with muscle-specific effects
Intramuscular fat (IMF) storage is a biological process with a strong impact on nutritional and technological properties of meat and also with rel- evant consequences on human health. The genetic ar- chitecture of IMF content and composition phenotypes has been thoroughly studied in pigs through the iden- tification of QTL and the estimation of genetic param- eters. A question that has not been elucidated yet is if the genetic determinants of IMF-related phenotypes are muscle specific or, conversely, have broad effects on the whole skeletal muscle compartment. We have ad- dressed this question by generating lipid QTL maps for 2 muscles with a high commercial value, gluteus medius (GM) and longissimus thoracis et lumborum (LTL), in a Duroc commercial population (n = 350). Our data support a lack of concordance between the GM and LTL QTL maps, suggesting that the effects of poly- morphisms influencing IMF, cholesterol, and fatty acid contents are modulated to some extent by complex spa- tial factors related to muscle location, metabolism, and function. These results have important implications on the implementation of genomic selection schemes aimed to improve the lipid profile of swine meat. © 2011 American Society of Animal Science, All rights reserved.
| Main Authors: | , , , , , , , |
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| Other Authors: | |
| Format: | artículo biblioteca |
| Language: | English |
| Published: |
American Society of Animal Science
2011-12-04
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| Subjects: | Fatty acid profile, Genetics of muscle lipids, Intramuscular fat, Pig, Quantitative trait locus, |
| Online Access: | http://hdl.handle.net/10261/50844 http://dx.doi.org/10.13039/501100004837 http://dx.doi.org/10.13039/100007652 http://dx.doi.org/10.13039/501100011104 |
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