Additional file 5 of Genetically predicted telomere length and Alzheimer’s disease endophenotypes: a Mendelian randomization study

Additional file 5: Supplementary Figure 1. Leave-one-out permutation analysis plot for AD signature among individuals at high genetic predisposition to AD obtained by leaving out the SNP indicated and repeating the Inverse-Variance Weighted method with the rest of the instrumental variables. Supplementary Figure 2. Leave-one-out permutation analysis plot for Aging signature among individuals at high genetic predisposition to AD, obtained by leaving out the SNP indicated and repeating the Inverse-Variance Weighted method with the rest of the instrumental variables. Supplementary Figure 3. Leave-one-out permutation analysis plot for Aβ ratio among APOE-ɛ4 non-carriers obtained by leaving out the SNP indicated and repeating the Inverse-Variance Weighted method with the rest of the instrumental variables. Supplementary Figure 4. Leave-one-out permutation analysis plot for NfL among APOE-ɛ4 non-carriers obtained by leaving out the SNP indicated and repeating the Inverse-Variance Weighted method with the rest of the instrumental variables. Supplementary Figure 5. Leave-one-out permutation analysis plot for p-tau among individuals at high genetic predisposition to AD, obtained by leaving out the SNP indicated and repeating the Inverse-Variance Weighted method with the rest of the instrumental variables.

Bibliographic Details

Main Authors:	Rodríguez-Fernández, Blanca, Vilor-Tejedor, Natalia, Arenaza-Urquijo, Eider M., Sánchez-Benavides, Gonzalo, Suárez-Calvet, Marc, Operto, Grégory, Minguillón, Carolina, Fauria, Karine, Kollmorgen, Gwendlyn, Suridjan, Ivonne, Castro de Moura, Manuel, Piñeyro, David, Esteller, Manel, Blennow, Kaj, Zetterberg, Henrik, De Vivo, Immaculata, Molinuevo, José Luis, Navarro, Arcadi, Gispert, Juan Domingo, Sala-Vila, Aleix, Crous-Bou, Marta
Format:	dataset biblioteca
Language:	English
Published:	Figshare 2022-11-08
Subjects:	Alzheimer’s disease, Cerebrospinal fluid biomarkers, Mendelian randomization, Neuroimaging, Polygenic risk score, Telomere length,
Online Access:	http://hdl.handle.net/10261/311633
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