Age and sex-associated variation in the multi-site microbiome of an entire social group of free-ranging rhesus macaques
[Background] An individual’s microbiome changes over the course of its lifetime, especially during infancy, and again in old age. Confounding factors such as diet and healthcare make it difficult to disentangle the interactions between age, health, and microbial changes in humans. Animal models present an excellent opportunity to study age- and sex-linked variation in the microbiome, but captivity is known to influence animal microbial abundance and composition, while studies of free-ranging animals are typically limited to studies of the fecal microbiome using samples collected non-invasively. Here, we analyze a large dataset of oral, rectal, and genital swabs collected from 105 free-ranging rhesus macaques (Macaca mulatta, aged 1 month-26 years), comprising one entire social group, from the island of Cayo Santiago, Puerto Rico. We sequenced 16S V4 rRNA amplicons for all samples.
Main Authors: | , , , , , , , , , , , , , , |
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Other Authors: | |
Format: | artículo biblioteca |
Language: | English |
Published: |
BioMed Central
2021-03-22
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Subjects: | Aging, Non-human primates, Genital microbiome, Oral microbiome, Gut microbiome, Sex differences, |
Online Access: | http://hdl.handle.net/10261/251045 http://dx.doi.org/10.13039/100012856 http://dx.doi.org/10.13039/100007631 http://dx.doi.org/10.13039/100000010 http://dx.doi.org/10.13039/100000002 http://dx.doi.org/10.13039/501100000270 http://dx.doi.org/10.13039/501100000038 http://dx.doi.org/10.13039/100006732 |
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Internet
http://hdl.handle.net/10261/251045http://dx.doi.org/10.13039/100012856
http://dx.doi.org/10.13039/100007631
http://dx.doi.org/10.13039/100000010
http://dx.doi.org/10.13039/100000002
http://dx.doi.org/10.13039/501100000270
http://dx.doi.org/10.13039/501100000038
http://dx.doi.org/10.13039/100006732