A comparative genomics multitool for scientific discovery and conservation
The Zoonomia Project is investigating the genomics of shared and specialized traits in eutherian mammals. Here we provide genome assemblies for 131 species, of which all but 9 are previously uncharacterized, and describe a whole-genome alignment of 240 species of considerable phylogenetic diversity, comprising representatives from more than 80% of mammalian families. We find that regions of reduced genetic diversity are more abundant in species at a high risk of extinction, discern signals of evolutionary selection at high resolution and provide insights from individual reference genomes. By prioritizing phylogenetic diversity and making data available quickly and without restriction, the Zoonomia Project aims to support biological discovery, medical research and the conservation of biodiversity.
Main Authors: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
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Format: | artículo biblioteca |
Published: |
Nature Publishing Group
2020-11-12
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Online Access: | http://hdl.handle.net/10261/236047 http://dx.doi.org/10.13039/501100002081 http://dx.doi.org/10.13039/501100004063 http://dx.doi.org/10.13039/501100000265 http://dx.doi.org/10.13039/501100003329 http://dx.doi.org/10.13039/100000002 http://dx.doi.org/10.13039/100000001 http://dx.doi.org/10.13039/501100000288 http://dx.doi.org/10.13039/100000014 http://dx.doi.org/10.13039/100000011 http://dx.doi.org/10.13039/100004440 http://dx.doi.org/10.13039/501100002809 http://dx.doi.org/10.13039/501100000781 http://dx.doi.org/10.13039/501100000780 http://dx.doi.org/10.13039/501100011033 http://dx.doi.org/10.13039/501100002341 http://dx.doi.org/10.13039/501100007051 |
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http://hdl.handle.net/10261/236047http://dx.doi.org/10.13039/501100002081
http://dx.doi.org/10.13039/501100004063
http://dx.doi.org/10.13039/501100000265
http://dx.doi.org/10.13039/501100003329
http://dx.doi.org/10.13039/100000002
http://dx.doi.org/10.13039/100000001
http://dx.doi.org/10.13039/501100000288
http://dx.doi.org/10.13039/100000014
http://dx.doi.org/10.13039/100000011
http://dx.doi.org/10.13039/100004440
http://dx.doi.org/10.13039/501100002809
http://dx.doi.org/10.13039/501100000781
http://dx.doi.org/10.13039/501100000780
http://dx.doi.org/10.13039/501100011033
http://dx.doi.org/10.13039/501100002341
http://dx.doi.org/10.13039/501100007051