Unraveling the effect of genomic structural changes in the rhesus macaque - implications for the adaptive role of inversions
[Background] By reshuffling genomes, structural genomic reorganizations provide genetic variation on which natural selection can work. Understanding the mechanisms underlying this process has been a long-standing question in evolutionary biology. In this context, our purpose in this study is to characterize the genomic regions involved in structural rearrangements between human and macaque genomes and determine their influence on meiotic recombination as a way to explore the adaptive role of genome shuffling in mammalian evolution.
Main Authors: | , , , |
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Other Authors: | |
Format: | artículo biblioteca |
Language: | English |
Published: |
BioMed Central
2014-06-26
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Subjects: | Genome shuffling, Inversions, Macaque, Recombination, Adaptation, Meiosis, Tandem repeats, Evolutionary breakpoints, |
Online Access: | http://hdl.handle.net/10261/115748 http://dx.doi.org/10.13039/501100003329 |
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