The Ablation of Sensory Neurons Expressing the Nav1.8 Sodium Channel Improves Glucose Homeostasis and Amplifies the GLP-1 Signaling in Obese Female Mice
Sensory neurons expressing the sodium channel Nav1.8 contain a repertoire of receptors for nutrient, hormonal, and inflammatory ligands. However, their function in key regulators of energy homeostasis control is not well understood and is completely unexplored in females.
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Main Authors: | Romaní Pérez, Marina, Bullich Vilarrubias, Clara, López Almela, Inmaculada, Sanz Herranz, Yolanda |
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Other Authors: | Agencia Estatal de Investigación (España) |
Format: | artículo biblioteca |
Language: | English |
Published: |
John Wiley & Sons
2023-12-01
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Subjects: | Nav1.8+ sensory neurons, Glucagon like peptide-1 (GLP-1), Obesity, Type 2 diabetes, |
Online Access: | http://hdl.handle.net/10261/341723 http://dx.doi.org/10.13039/501100000780 http://dx.doi.org/10.13039/501100011033 https://api.elsevier.com/content/abstract/scopus_id/85178245834 |
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