The Ablation of Sensory Neurons Expressing the Nav1.8 Sodium Channel Improves Glucose Homeostasis and Amplifies the GLP-1 Signaling in Obese Female Mice

Sensory neurons expressing the sodium channel Nav1.8 contain a repertoire of receptors for nutrient, hormonal, and inflammatory ligands. However, their function in key regulators of energy homeostasis control is not well understood and is completely unexplored in females.

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Bibliographic Details
Main Authors: Romaní Pérez, Marina, Bullich Vilarrubias, Clara, López Almela, Inmaculada, Sanz Herranz, Yolanda
Other Authors: Agencia Estatal de Investigación (España)
Format: artículo biblioteca
Language:English
Published: John Wiley & Sons 2023-12-01
Subjects:Nav1.8+ sensory neurons, Glucagon like peptide-1 (GLP-1), Obesity, Type 2 diabetes,
Online Access:http://hdl.handle.net/10261/341723
http://dx.doi.org/10.13039/501100000780
http://dx.doi.org/10.13039/501100011033
https://api.elsevier.com/content/abstract/scopus_id/85178245834
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