Cofactors of wheat-dependent exercise-induced anaphylaxis do not increase highly individual gliadin absorption in healthy volunteers

[Background] In wheat-dependent exercise-induced anaphylaxis (WDEIA), cofactors such as exercise, acetylsalicylic acid (ASA), alcohol or unfavorable climatic conditions are required to elicit a reaction to wheat products. The mechanism of action of these cofactors is unknown, but an increase of gliadin absorption has been speculated. Our objectives were to study gliadin absorption with and without cofactors and to correlate plasma gliadin levels with factors influencing protein absorption in healthy volunteers.

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Bibliographic Details
Main Authors: Scherf, Katharina A., Lindenau, Ann-Christin, Valentini, Luzia, Collado, María Carmen, García Mantrana, Izaskun, Christensen, Morten, Tomsitz, Dirk, Kugler, Claudia, Biedermann, Tilo, Brockow, Knut
Other Authors: German Research Foundation
Format: artículo biblioteca
Language:English
Published: BioMed Central 2019-03-25
Subjects:Cofactor, Gliadin, Gluten, Gut microbiota, Intestinal permeability, Wheat allergy, Wheat-dependent exercise induced anaphylaxis (WDEIA), Zonulin,
Online Access:http://hdl.handle.net/10261/178966
http://dx.doi.org/10.13039/501100005713
http://dx.doi.org/10.13039/501100001659
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