Enhanced glycosyl hydrolase production in Aspergillus nidulans using transcription factor engineering approaches
[Background] Engineered fungi are attractive platforms for the production of plant cell wall hydrolytic enzymes which, among other biotechnological applications, are required for the efficient conversion of biomass to glucose and other fermentable sugars. As a fungal model system, Aspergillus nidulans provides genetic tools that are of relevance in this context and potentially applicable to industrially important filamentous fungi. The goal of this study is to assess the utility of A. nidulans as a host for recombinant protein production.
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| Main Authors: | , |
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| Other Authors: | |
| Format: | artículo biblioteca |
| Published: |
BioMed Central
2014-07-04
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| Subjects: | Ambient pH regulation, Fungal cell factories, PalA/PacC, Xylan/xylose regulator (XlnR), XlnR-xlnp expression system, Protein production, Aspergillus nidulans, Plant cell wall degrading enzymes, Endo-1,4-β-Xylanase, α-L-rhamnosidase, |
| Online Access: | http://hdl.handle.net/10261/110773 http://dx.doi.org/10.13039/501100004837 http://dx.doi.org/10.13039/501100000780 http://dx.doi.org/10.13039/501100007273 http://dx.doi.org/10.13039/501100000921 |
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