Development of a dual recombinant vaccine to protect small ruminants against peste-des-petits-ruminants virus and capripoxvirus infections

Development of a dual recombinant vaccine to protect small ruminants against peste-des-petits-ruminants virus and capripoxvirus infections

A recombinant capripoxvirus vaccine containing a cDNA of the peste-des-petits-ruminants virus (PPRV) fusion protein gene was constructed. A quick and efficient method was used to select a highly purified recombinant virus clone. A trial showed that a dose of this recombinant as low as 0.1 PFU protected goats against challenge with a virulent PPRV strain.

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Bibliographic Details
Main Authors: Berhe, G., Minet, Cécile, Le Goff, Christian, Barrett, Thomas, Ngangnou, A., Grillet, Colette, Libeau, Geneviève, Fleming, M., Black, D.N., Diallo, Adama
Format: article biblioteca
Language:eng
Subjects:L73 - Maladies des animaux, peste des petits ruminants, virologie, capripoxvirus, vaccin synthétique, http://aims.fao.org/aos/agrovoc/c_16789, http://aims.fao.org/aos/agrovoc/c_8259, http://aims.fao.org/aos/agrovoc/c_1284, http://aims.fao.org/aos/agrovoc/c_27865,
Online Access:http://agritrop.cirad.fr/513066/
http://agritrop.cirad.fr/513066/1/513066.pdf
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http://agritrop.cirad.fr/513066/
http://agritrop.cirad.fr/513066/1/513066.pdf

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