Immune response to Dermatophilus congolensis infections
Complex mechanisms underly the establishment of dermatophilosis, an exudative and proliferative skin disease of ruminants. This multicomponent system involves the bacterium Dermatophilus congolensis, transmission by various routes including flies, host genetic factors and immunosuppression by Amblyomma variegatum ticks. Here, Nick Ambrose and colleagues summarize recent evidence for an association between A. variegatum and severe chronic dermatophilosis in cattle. Breed-based differences in resistance to dermatophilosis are probably related to immunity to ticks or resistance to the immunosuppressive effects of ticks. Immunity to dermatophilosis might involve non-classic responses mediated by CD1 antigen presentation and ybeta T cells. Progress towards vaccination is further complicated by strain-specific acquired immunity to D. congolensis.
| Main Authors: | , , |
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| Format: | article biblioteca |
| Language: | eng |
| Subjects: | L73 - Maladies des animaux, L72 - Organismes nuisibles des animaux, Dermatophilus congolensis, maladie infectieuse, réponse immunitaire, Amblyomma variegatum, résistance aux organismes nuisibles, ruminant, http://aims.fao.org/aos/agrovoc/c_27184, http://aims.fao.org/aos/agrovoc/c_34024, http://aims.fao.org/aos/agrovoc/c_3799, http://aims.fao.org/aos/agrovoc/c_23890, http://aims.fao.org/aos/agrovoc/c_5731, http://aims.fao.org/aos/agrovoc/c_6695, |
| Online Access: | http://agritrop.cirad.fr/401321/ http://agritrop.cirad.fr/401321/1/401321.pdf |
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