A shared perspective on in vitro and in vivo models to assay intestinal transepithelial transport of food compounds

Assessing nutrient bioavailability is complex, as the process involves multiple digestion steps, several cellular environments, and regulatory-metabolic mechanisms. Several in vitro models of different physiological relevance are used to study nutrient absorption, providing significant challenges in data evaluation. However, such in vitro models are needed for mechanistic studies as well as to screen for biological functionality of the food structures designed. This collaborative work aims to put into perspective the wide-range of models to assay the permeability of food compounds considering the particular nature of the different molecules, and, where possible, in vivo data are provided for comparison.

Bibliographic Details

Main Authors:	Hevia, Arancha, Ruas-Madiedo, Patricia, Faria, Miguel Angelo, Petit, Valérie, Alves, Bruna, Alvito, Paula, Arranz, Elena, Bastiaan-Net, Shanna, Corredig, Milena, Dijk, Wieneke, Dupont, Didier, Giblin, Linda, Graf, Brigitte Anna, Kondrashina, Alina, Ramos, Helena, Ruíz García, Lorena, Santos-Hernández, Marta, Soriano-Romaní, Laura, Tomás-Cobos, Lidia, Vivanco-Maroto, Santiaga María, Recio, Isidra, Miralles, Beatriz
Other Authors:	Fundação para a Ciência e a Tecnologia (Portugal)
Format:	artículo biblioteca
Language:	English
Published:	American Chemical Society 2023
Subjects:	Intestines, Transepithelial transport, Nutrient bioavailability, Food compounds,
Online Access:	http://hdl.handle.net/10261/340682
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