Supplementary Materials for Supplementation with the symbiotic formulation Prodefen® increases neuronal nitric oxide synthase and decreases oxidative stress in superior mesenteric artery from spontaneously hypertensive rats
The supporting information: Figure S1: (a) Systolic blood pressure from WKY, SHR-Ctrl and SHR-SYNB animals (Mean + S.E.M.; n = 11–14 animals each group) expressed in mm Hg. One-way ANOVA, followed by a Tukey post-hoc test was used as a statistical analysis. * p < 0.05 WKY vs. SHR-Ctrl; # p < 0.05 SHR-Ctrl vs. SHR-SYNB. + p < 0.05 WKY vs. SHR-SYNB. (b) EFS-induced NO release in mesenteric segments from WKY, SHR-Ctrl and SHR-SYNB animals (Mean + S.E.M.; n = 11–14 animals each group) expressed in arbitrary fluorescence units (A.F.U.)/mg tissue. One-way ANOVA, followed by a Tukey post-hoc test was used as a statistical analysis. * p < 0.05 WKY vs. SHR-Ctrl; # p < 0.05 SHR-Ctrl vs. SHR-SYNB. + p < 0.05 WKY vs. SHR-SYNB (c) Analysis of the functional role of neuronal NO on EFS-induced vasoconstriction by preincubation with the unspecific nitric oxide synthase (NOS) inhibitor L-NAME, in mesenteric arteries WKY rats. Results (mean ± S.E.M.) are expressed as a percentage of previous tone induced by KCl. n = 6 segments from different animals in each ex-perimental group.
| Main Authors: | , , , , , , , , , |
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| Format: | dataset biblioteca |
| Language: | English |
| Published: |
Multidisciplinary Digital Publishing Institute
2022
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| Online Access: | http://hdl.handle.net/10261/311227 |
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