Bioactive properties of blueberry extracts obtained by different drying techniques against Helicobacter pylori

Bioactive properties of blueberry extracts obtained by different drying techniques against Helicobacter pylori

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Trabajo presentado al 3rd International Electronic Conference on Foods: Food, Microbiome, and Health, celebrado on-line del 1 al 15 de octubre de 2022.

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Main Authors: Silván, José Manuel, Michalska-Ciechanowska, Anna, Villalva, Marisol, Brzezowska, Jessica, Martínez-Rodríguez, Adolfo J., Díaz, Soledad
Other Authors: Ministerio de Ciencia, Innovación y Universidades (España)
Format: póster de congreso biblioteca
Language:English
Published: 2022
Online Access:http://hdl.handle.net/10261/285070
http://dx.doi.org/10.13039/501100011033
http://dx.doi.org/10.13039/501100003329
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spelling dig-cial-es-10261-2850702023-02-06T08:50:48Z Bioactive properties of blueberry extracts obtained by different drying techniques against Helicobacter pylori Silván, José Manuel Michalska-Ciechanowska, Anna Villalva, Marisol Brzezowska, Jessica Martínez-Rodríguez, Adolfo J. Díaz, Soledad Ministerio de Ciencia, Innovación y Universidades (España) Agencia Estatal de Investigación (España) Ministerio de Economía y Competitividad (España) Trabajo presentado al 3rd International Electronic Conference on Foods: Food, Microbiome, and Health, celebrado on-line del 1 al 15 de octubre de 2022. Helicobacter pylori (H. pylori) is one of the most successful and prevalent human pathogens that infect more than 50% of the world¿s population. Chronic inflammation of the gastric mucosa is one of the main consequences of this infection and is associated with the risk of gastric cancer. Currently, Due to this high correlation between H. pylori infection and development of gastric cancer, most therapeutic international guidelines aim to eradicate this pathogen using a combination of antibiotics with a proton pump inhibitor in a triple or quadruple therapy. However, resistant strains have increased significantly, requiring new therapeutic tools. Blueberries are rich in different bioactive compounds with antibacterial and anti-inflammatory properties that could contribute to reduce the problems associated with H. pylori infection. The objective of the present work was to evaluate the antibacterial and anti-inflammatory properties of different blueberry extracts obtained by different drying methods against H. pylori infection. Results showed that all blueberry extracts showed antibacterial activity against H. pylori, some of these extracts being bactericidal, while the rest reduced bacterial growth by more than 5 log CFU/mL. Bluecrop extracts were the most active, because all extracts obtained by the different drying methods resulted bactericidal. Extracts obtained by vacuum drying (VD) at 50ºC was the most effective since the extracts of the three varieties were bactericidal. Regarding anti-inflammatory activity, all blueberry extracts reduced IL-8 production in H. pylori-infected AGS cells. Bluecrop extracts obtained by the VD at 70ºC and 90ºC reduced IL-8 production by 30% and 32%, respectively. These results suggest that blueberry extracts used in the present work and obtained by different drying methods could be a useful alternative in the control of H. pylori and in the modulation of the gastric inflammatory process induced in H. pylori infection. This research was funded by MINECO (Spain), Project HELIFOOD (AGL2017-89566-R). Peer reviewed 2022-12-16T12:37:06Z 2022-12-16T12:37:06Z 2022 póster de congreso 3rd International Electronic Conference on Foods (2022) http://hdl.handle.net/10261/285070 http://dx.doi.org/10.13039/501100011033 http://dx.doi.org/10.13039/501100003329 en #PLACEHOLDER_PARENT_METADATA_VALUE# info:eu-repo/grantAgreement/AEI/Plan Estatal de Investigación Científica y Técnica y de Innovación 2013-2016/AGL2017-89566-R/ES/REVALORIZACION DE SUBPRODUCTOS DE LA INDUSTRIA ALIMENTARIA COMO FUENTE DE COMPUESTOS BIOACTIVOS UTILES PARA LA MITIGACION DE LA INFECCION HUMANA POR HELICOBACTER PYLORI/ Publisher's version Sí open application/pdf
institution CIAL ES
collection DSpace
country España
countrycode ES
component Bibliográfico
access En linea
databasecode dig-cial-es
tag biblioteca
region Europa del Sur
libraryname Biblioteca del CIAL España
language English
description Trabajo presentado al 3rd International Electronic Conference on Foods: Food, Microbiome, and Health, celebrado on-line del 1 al 15 de octubre de 2022.
author2 Ministerio de Ciencia, Innovación y Universidades (España)
author_facet Ministerio de Ciencia, Innovación y Universidades (España)
Silván, José Manuel
Michalska-Ciechanowska, Anna
Villalva, Marisol
Brzezowska, Jessica
Martínez-Rodríguez, Adolfo J.
Díaz, Soledad
format póster de congreso
author Silván, José Manuel
Michalska-Ciechanowska, Anna
Villalva, Marisol
Brzezowska, Jessica
Martínez-Rodríguez, Adolfo J.
Díaz, Soledad
spellingShingle Silván, José Manuel
Michalska-Ciechanowska, Anna
Villalva, Marisol
Brzezowska, Jessica
Martínez-Rodríguez, Adolfo J.
Díaz, Soledad
Bioactive properties of blueberry extracts obtained by different drying techniques against Helicobacter pylori
author_sort Silván, José Manuel
title Bioactive properties of blueberry extracts obtained by different drying techniques against Helicobacter pylori
title_short Bioactive properties of blueberry extracts obtained by different drying techniques against Helicobacter pylori
title_full Bioactive properties of blueberry extracts obtained by different drying techniques against Helicobacter pylori
title_fullStr Bioactive properties of blueberry extracts obtained by different drying techniques against Helicobacter pylori
title_full_unstemmed Bioactive properties of blueberry extracts obtained by different drying techniques against Helicobacter pylori
title_sort bioactive properties of blueberry extracts obtained by different drying techniques against helicobacter pylori
publishDate 2022
url http://hdl.handle.net/10261/285070
http://dx.doi.org/10.13039/501100011033
http://dx.doi.org/10.13039/501100003329
work_keys_str_mv AT silvanjosemanuel bioactivepropertiesofblueberryextractsobtainedbydifferentdryingtechniquesagainsthelicobacterpylori
AT michalskaciechanowskaanna bioactivepropertiesofblueberryextractsobtainedbydifferentdryingtechniquesagainsthelicobacterpylori
AT villalvamarisol bioactivepropertiesofblueberryextractsobtainedbydifferentdryingtechniquesagainsthelicobacterpylori
AT brzezowskajessica bioactivepropertiesofblueberryextractsobtainedbydifferentdryingtechniquesagainsthelicobacterpylori
AT martinezrodriguezadolfoj bioactivepropertiesofblueberryextractsobtainedbydifferentdryingtechniquesagainsthelicobacterpylori
AT diazsoledad bioactivepropertiesofblueberryextractsobtainedbydifferentdryingtechniquesagainsthelicobacterpylori
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