Foodomics evaluation of bioactive compounds in foods

Foodomics involves the study of food and nutrition domains through the application and integration of advanced omics technologies, such as transcriptomics, proteomics and metabolomics. This integration, together with biostatistics, chemometrics and bioinformatics tools allows the evaluation of complex biological systems, like those involved in the underlying mechanisms of bioactive food compounds that help to interpret the association between dietary exposure and health. In this review, we present a critical discussion of the recent developments in Foodomics approaches (including metabolomics, proteomics and transcriptomics) to understand the bioactivity of food and food ingredients on health as well as for the discovery of novel biomarkers related to such activity.

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Bibliographic Details
Main Authors: Valdés, Alberto, Cifuentes, Alejandro, León, Carlos
Other Authors: Ministerio de Economía y Competitividad (España)
Format: artículo biblioteca
Language:English
Published: Elsevier 2017
Subjects:Foodomics, Food science, Bioactive compounds, Proteomics, Metabolomics, Transcriptomics, Cancer, Neurodegenerative disease,
Online Access:http://hdl.handle.net/10261/194074
http://dx.doi.org/10.13039/501100003329
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spelling dig-cial-es-10261-1940742019-11-08T03:11:51Z Foodomics evaluation of bioactive compounds in foods Valdés, Alberto Cifuentes, Alejandro León, Carlos Ministerio de Economía y Competitividad (España) Foodomics Food science Bioactive compounds Proteomics Metabolomics Transcriptomics Cancer Neurodegenerative disease Foodomics involves the study of food and nutrition domains through the application and integration of advanced omics technologies, such as transcriptomics, proteomics and metabolomics. This integration, together with biostatistics, chemometrics and bioinformatics tools allows the evaluation of complex biological systems, like those involved in the underlying mechanisms of bioactive food compounds that help to interpret the association between dietary exposure and health. In this review, we present a critical discussion of the recent developments in Foodomics approaches (including metabolomics, proteomics and transcriptomics) to understand the bioactivity of food and food ingredients on health as well as for the discovery of novel biomarkers related to such activity. This work was supported by projects AGL2014-53609-P and SAF2013-43475. Peer reviewed 2019-11-06T12:29:29Z 2019-11-06T12:29:29Z 2017 artículo http://purl.org/coar/resource_type/c_6501 Trends in Analytical Chemistry 96: 2-13 (2017) 0165-9936 http://hdl.handle.net/10261/194074 10.1016/j.trac.2017.06.004 http://dx.doi.org/10.13039/501100003329 en #PLACEHOLDER_PARENT_METADATA_VALUE# #PLACEHOLDER_PARENT_METADATA_VALUE# info:eu-repo/grantAgreement/MINECO/Plan Estatal de Investigación Científica y Técnica y de Innovación 2013-2016/AGL2014-53609-P info:eu-repo/grantAgreement/MINECO/Plan Estatal de Investigación Científica y Técnica y de Innovación 2013-2016/SAF2013-43475-R https://doi.org/10.1016/j.trac.2017.06.004 Sí none Elsevier
institution CIAL ES
collection DSpace
country España
countrycode ES
component Bibliográfico
access En linea
databasecode dig-cial-es
tag biblioteca
region Europa del Sur
libraryname Biblioteca del CIAL España
language English
topic Foodomics
Food science
Bioactive compounds
Proteomics
Metabolomics
Transcriptomics
Cancer
Neurodegenerative disease
Foodomics
Food science
Bioactive compounds
Proteomics
Metabolomics
Transcriptomics
Cancer
Neurodegenerative disease
spellingShingle Foodomics
Food science
Bioactive compounds
Proteomics
Metabolomics
Transcriptomics
Cancer
Neurodegenerative disease
Foodomics
Food science
Bioactive compounds
Proteomics
Metabolomics
Transcriptomics
Cancer
Neurodegenerative disease
Valdés, Alberto
Cifuentes, Alejandro
León, Carlos
Foodomics evaluation of bioactive compounds in foods
description Foodomics involves the study of food and nutrition domains through the application and integration of advanced omics technologies, such as transcriptomics, proteomics and metabolomics. This integration, together with biostatistics, chemometrics and bioinformatics tools allows the evaluation of complex biological systems, like those involved in the underlying mechanisms of bioactive food compounds that help to interpret the association between dietary exposure and health. In this review, we present a critical discussion of the recent developments in Foodomics approaches (including metabolomics, proteomics and transcriptomics) to understand the bioactivity of food and food ingredients on health as well as for the discovery of novel biomarkers related to such activity.
author2 Ministerio de Economía y Competitividad (España)
author_facet Ministerio de Economía y Competitividad (España)
Valdés, Alberto
Cifuentes, Alejandro
León, Carlos
format artículo
topic_facet Foodomics
Food science
Bioactive compounds
Proteomics
Metabolomics
Transcriptomics
Cancer
Neurodegenerative disease
author Valdés, Alberto
Cifuentes, Alejandro
León, Carlos
author_sort Valdés, Alberto
title Foodomics evaluation of bioactive compounds in foods
title_short Foodomics evaluation of bioactive compounds in foods
title_full Foodomics evaluation of bioactive compounds in foods
title_fullStr Foodomics evaluation of bioactive compounds in foods
title_full_unstemmed Foodomics evaluation of bioactive compounds in foods
title_sort foodomics evaluation of bioactive compounds in foods
publisher Elsevier
publishDate 2017
url http://hdl.handle.net/10261/194074
http://dx.doi.org/10.13039/501100003329
work_keys_str_mv AT valdesalberto foodomicsevaluationofbioactivecompoundsinfoods
AT cifuentesalejandro foodomicsevaluationofbioactivecompoundsinfoods
AT leoncarlos foodomicsevaluationofbioactivecompoundsinfoods
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