Production and bioactivity of oligosaccharides derived from lactose

In an attempt to offer a broad overview on lactose applications as a source of bioactive carbohydrates, in this chapter, the authors have collected the most recent investigations on methods to produce these compounds, which have a positive effect on gut microbiota. Chemical and biological productions of tagatose, lactulose, lactosucrose, lactulosucrose, and galactooligosaccharides, among others, have been described. Moreover, their main uses, based on their bioactivity and techno-functional properties, are also shown together with a brief description of purification methods of the mixtures obtained. Particular attention has been paid to a new generation of oligosaccharides derived from lactulose with a potential prebiotic effect, which is even better than that of this recognised functional ingredient. These novel oligosaccharides, mainly composed of 6′-galactosyl lactulose and 1-galactosyl lactulose, can be obtained with good yields either by transgalactosylation of lactulose or by chemical isomerisation under basic media of galactooligosaccharides—the latter constitutes a good and economic option.

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Bibliographic Details
Main Authors: Villamiel, Mar, Montilla, Antonia, Olano, Agustín, Corzo, Nieves
Other Authors: Comunidad de Madrid
Format: capítulo de libro biblioteca
Published: Wiley-Blackwell 2014
Subjects:Prebiotic properties, Lactulosucrose, 1-galactosyl lactulose, 6′-galactosyl lactulose, Galactooligosaccharides, Lactose derivatives, Chemical and enzymatic isomerisation, Transglycosylation,
Online Access:http://hdl.handle.net/10261/126743
http://dx.doi.org/10.13039/501100004837
http://dx.doi.org/10.13039/501100000780
http://dx.doi.org/10.13039/100012818
http://dx.doi.org/10.13039/501100011698
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