Capability of Lactobacillus plantarum IFPL935 to catabolize Flavan-3-ol compounds and complex phenolic extracts
Lactobacillus plantarum IFPL935 was incubated with individual monomeric flavan-3-ols and dimeric A-and B-type procyanidins to identify new metabolites and to determine the effect of compound structural features on bacterial growth and catabolism. Complex extracts rich in A-type proanthocyanidins and phenolic acids from cranberry were also tested. The results showed that L. plantarum IFPL935 exhibited higher resistance to nongalloylated monomeric flavan-3-ols, A-type dimeric procyanidins, and cranberry extract than to (-)-epicatechin-3-O- gallate and B-type dimeric procyanidins. Despite these findings, the strain was capable of rapidly degrading (-)-epicatechin-3-O-gallate, but not A- or B-type dimeric procyanidins. However, it was able to produce large changes in the phenolic profile of the cranberry extract mainly due to the catabolism of hydroxycinnamic and hydroxybenzoic acids. Of most relevance was the fact that L. plantarum IFPL935 cleaved the heterocyclic ring of monomeric flavan-3-ols, giving rise to 1-(3',4'-dihydroxyphenyl)-3-(2>,4>,6>- trihydroxyphenyl)propan-2-ol, activity exhibited by only a few human intestinal bacteria. © 2012 American Chemical Society.
Main Authors: | , , , , , , |
---|---|
Other Authors: | |
Format: | artículo biblioteca |
Published: |
American Chemical Society
2012
|
Subjects: | Cranberry extract, Grape seed extract, A-type procyanidins, B-type procyanidins, Flavan-3-ols, Microbial catabolism, Lactobacillus, |
Online Access: | http://hdl.handle.net/10261/101249 http://dx.doi.org/10.13039/501100004837 http://dx.doi.org/10.13039/501100000780 http://dx.doi.org/10.13039/501100003339 http://dx.doi.org/10.13039/100012818 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
id |
dig-cial-es-10261-101249 |
---|---|
record_format |
koha |
spelling |
dig-cial-es-10261-1012492018-09-19T08:29:26Z Capability of Lactobacillus plantarum IFPL935 to catabolize Flavan-3-ol compounds and complex phenolic extracts Sánchez-Patán, Fernando Tabasco, Raquel Monagas Juan, María Josefina Requena, Teresa Peláez, Carmen Moreno-Arribas, M. Victoria Bartolomé, Begoña Comunidad de Madrid Ministerio de Ciencia e Innovación (España) European Commission Consejo Superior de Investigaciones Científicas (España) Cranberry extract Grape seed extract A-type procyanidins B-type procyanidins Flavan-3-ols Microbial catabolism Lactobacillus Lactobacillus plantarum IFPL935 was incubated with individual monomeric flavan-3-ols and dimeric A-and B-type procyanidins to identify new metabolites and to determine the effect of compound structural features on bacterial growth and catabolism. Complex extracts rich in A-type proanthocyanidins and phenolic acids from cranberry were also tested. The results showed that L. plantarum IFPL935 exhibited higher resistance to nongalloylated monomeric flavan-3-ols, A-type dimeric procyanidins, and cranberry extract than to (-)-epicatechin-3-O- gallate and B-type dimeric procyanidins. Despite these findings, the strain was capable of rapidly degrading (-)-epicatechin-3-O-gallate, but not A- or B-type dimeric procyanidins. However, it was able to produce large changes in the phenolic profile of the cranberry extract mainly due to the catabolism of hydroxycinnamic and hydroxybenzoic acids. Of most relevance was the fact that L. plantarum IFPL935 cleaved the heterocyclic ring of monomeric flavan-3-ols, giving rise to 1-(3',4'-dihydroxyphenyl)-3-(2>,4>,6>- trihydroxyphenyl)propan-2-ol, activity exhibited by only a few human intestinal bacteria. © 2012 American Chemical Society. This work has been funded by the Spanish Ministry for Science and Innovation (AGL2009-13361-C02-00, AGL2010-17499, and CSD2007-00063 Consolider Ingenio 2010 FUN-C-FOOD Projects), the Comunidad de Madrid (ALIBIRD P2009/AGR- 1469 Project), and CYTED (IBEROFUN 110AC0386). F.S.-P. is the recipient of a contract from the JAE-Doc Program (CSIC). R.T. thanks the Danone Institute for a fellowship award. Peer Reviewed 2014-08-27T07:27:08Z 2014-08-27T07:27:08Z 2012 2014-08-27T07:27:08Z artículo http://purl.org/coar/resource_type/c_6501 doi: 10.1021/jf3006867 issn: 0021-8561 e-issn: 1520-5118 Journal of Agricultural and Food Chemistry 60(29): 7142-7151 (2012) http://hdl.handle.net/10261/101249 10.1021/jf3006867 http://dx.doi.org/10.13039/501100004837 http://dx.doi.org/10.13039/501100000780 http://dx.doi.org/10.13039/501100003339 http://dx.doi.org/10.13039/100012818 #PLACEHOLDER_PARENT_METADATA_VALUE# S2009/AGR-1469/ALIBIRD none American Chemical Society |
institution |
CIAL ES |
collection |
DSpace |
country |
España |
countrycode |
ES |
component |
Bibliográfico |
access |
En linea |
databasecode |
dig-cial-es |
tag |
biblioteca |
region |
Europa del Sur |
libraryname |
Biblioteca del CIAL España |
topic |
Cranberry extract Grape seed extract A-type procyanidins B-type procyanidins Flavan-3-ols Microbial catabolism Lactobacillus Cranberry extract Grape seed extract A-type procyanidins B-type procyanidins Flavan-3-ols Microbial catabolism Lactobacillus |
spellingShingle |
Cranberry extract Grape seed extract A-type procyanidins B-type procyanidins Flavan-3-ols Microbial catabolism Lactobacillus Cranberry extract Grape seed extract A-type procyanidins B-type procyanidins Flavan-3-ols Microbial catabolism Lactobacillus Sánchez-Patán, Fernando Tabasco, Raquel Monagas Juan, María Josefina Requena, Teresa Peláez, Carmen Moreno-Arribas, M. Victoria Bartolomé, Begoña Capability of Lactobacillus plantarum IFPL935 to catabolize Flavan-3-ol compounds and complex phenolic extracts |
description |
Lactobacillus plantarum IFPL935 was incubated with individual monomeric flavan-3-ols and dimeric A-and B-type procyanidins to identify new metabolites and to determine the effect of compound structural features on bacterial growth and catabolism. Complex extracts rich in A-type proanthocyanidins and phenolic acids from cranberry were also tested. The results showed that L. plantarum IFPL935 exhibited higher resistance to nongalloylated monomeric flavan-3-ols, A-type dimeric procyanidins, and cranberry extract than to (-)-epicatechin-3-O- gallate and B-type dimeric procyanidins. Despite these findings, the strain was capable of rapidly degrading (-)-epicatechin-3-O-gallate, but not A- or B-type dimeric procyanidins. However, it was able to produce large changes in the phenolic profile of the cranberry extract mainly due to the catabolism of hydroxycinnamic and hydroxybenzoic acids. Of most relevance was the fact that L. plantarum IFPL935 cleaved the heterocyclic ring of monomeric flavan-3-ols, giving rise to 1-(3',4'-dihydroxyphenyl)-3-(2>,4>,6>- trihydroxyphenyl)propan-2-ol, activity exhibited by only a few human intestinal bacteria. © 2012 American Chemical Society. |
author2 |
Comunidad de Madrid |
author_facet |
Comunidad de Madrid Sánchez-Patán, Fernando Tabasco, Raquel Monagas Juan, María Josefina Requena, Teresa Peláez, Carmen Moreno-Arribas, M. Victoria Bartolomé, Begoña |
format |
artículo |
topic_facet |
Cranberry extract Grape seed extract A-type procyanidins B-type procyanidins Flavan-3-ols Microbial catabolism Lactobacillus |
author |
Sánchez-Patán, Fernando Tabasco, Raquel Monagas Juan, María Josefina Requena, Teresa Peláez, Carmen Moreno-Arribas, M. Victoria Bartolomé, Begoña |
author_sort |
Sánchez-Patán, Fernando |
title |
Capability of Lactobacillus plantarum IFPL935 to catabolize Flavan-3-ol compounds and complex phenolic extracts |
title_short |
Capability of Lactobacillus plantarum IFPL935 to catabolize Flavan-3-ol compounds and complex phenolic extracts |
title_full |
Capability of Lactobacillus plantarum IFPL935 to catabolize Flavan-3-ol compounds and complex phenolic extracts |
title_fullStr |
Capability of Lactobacillus plantarum IFPL935 to catabolize Flavan-3-ol compounds and complex phenolic extracts |
title_full_unstemmed |
Capability of Lactobacillus plantarum IFPL935 to catabolize Flavan-3-ol compounds and complex phenolic extracts |
title_sort |
capability of lactobacillus plantarum ifpl935 to catabolize flavan-3-ol compounds and complex phenolic extracts |
publisher |
American Chemical Society |
publishDate |
2012 |
url |
http://hdl.handle.net/10261/101249 http://dx.doi.org/10.13039/501100004837 http://dx.doi.org/10.13039/501100000780 http://dx.doi.org/10.13039/501100003339 http://dx.doi.org/10.13039/100012818 |
work_keys_str_mv |
AT sanchezpatanfernando capabilityoflactobacillusplantarumifpl935tocatabolizeflavan3olcompoundsandcomplexphenolicextracts AT tabascoraquel capabilityoflactobacillusplantarumifpl935tocatabolizeflavan3olcompoundsandcomplexphenolicextracts AT monagasjuanmariajosefina capabilityoflactobacillusplantarumifpl935tocatabolizeflavan3olcompoundsandcomplexphenolicextracts AT requenateresa capabilityoflactobacillusplantarumifpl935tocatabolizeflavan3olcompoundsandcomplexphenolicextracts AT pelaezcarmen capabilityoflactobacillusplantarumifpl935tocatabolizeflavan3olcompoundsandcomplexphenolicextracts AT morenoarribasmvictoria capabilityoflactobacillusplantarumifpl935tocatabolizeflavan3olcompoundsandcomplexphenolicextracts AT bartolomebegona capabilityoflactobacillusplantarumifpl935tocatabolizeflavan3olcompoundsandcomplexphenolicextracts |
_version_ |
1777671152174366720 |