The advancements, challenges and future implications of the CRISPR/Cas9 system in swine research
Clustered regularly interspaced short palindromic repeats/CRISPR associated protein 9 (CRISPR/Cas9) genome editing technology has dramatically influenced swine research by enabling the production of high-quality disease-resistant pig breeds, thus improving yields. Additionally, CRISPR/Cas9 has been used extensively in pigs as one of the tools in biomedical research. In this review, we present the advancements of the CRISPR/Cas9 system in swine research such as animal breeding, vaccine development, xenotransplantation, and disease modelling. We also highlight the current challenges and some potential applications of the CRISPR/Cas9 technologies.
Main Authors: | , , , , , , , , , , , , , |
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Format: | Journal Article biblioteca |
Language: | English |
Published: |
Elsevier
2021-05
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Subjects: | swine, research, genomics, crispr, |
Online Access: | https://hdl.handle.net/10568/113738 https://doi.org/10.1016/j.jgg.2021.03.015 |
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