Toxische Wirkung von Schadstoffen auf Fischzellen. Bestimmung von DNA-Strangbrüchen mit dem Comet-Assay
The alkaline comet assay is a method of detecting DNA strand breaks and alkali labile sites in individual cells. The method was used to detect DNA strand breaks in isolated blood cells (leukocytes) of carp (Cyprius carpio). DNA damage have been induced by exposure of the cells to sediment extract. Therefore comet assay can be applied as in vitro bioassay for investigations on toxicity of marine sediments.
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| Main Author: | |
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| Format: | article biblioteca |
| Language: | German |
| Published: |
1998
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| Subjects: | Environment, Chemistry, marine environment, reproductive capacity, environmental stress, biomarker, gentoxic effects, |
| Online Access: | http://hdl.handle.net/1834/21076 |
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