Biodegradable Mats for the Design of Bifunctional Biosensors for Glucose Detection in Urine.

Abstract: We introduce a bifunctional architecture to construct biosensors on solution-blow spinning fiber mats of polylactic acid (PLA) and polyethylene glycol (PEG). PLA/PEG mats acted as substrate for printing electrodes and as matrix to immobilize glucose oxidase (GOx). Prussian Blue nanoparticles (PB) decorated working electrodes to detect H2O2 from enzymatic catalysis at a low applied potential (0 V vs Ag/AgCl) with detection limit of 0.197 mM. The inexpensive bifunctional device (<US $0.25 per unit) exhibited a rapid response, long lifetime and performance similiar to the standard method for glucose monitoring in human urine samples. The PLA/PEG mats are sustainable alternative for biosensing and wearable applications.

Bibliographic Details

Main Authors:	GOMES, N. O., PASCHOALIN, R. T., BILLATO, S., SORIGOTTI, A. R., FARINAS, C. S., MATTOSO, L. H. C., MACHADO, S. A. S., OLIVEIRA JR, O. N., RAYMUNDO-PEREIRA, P. A.
Other Authors:	CRISTIANE SANCHEZ FARINAS, CNPDIA; LUIZ HENRIQUE CAPPARELLI MATTOSO, CNPDIA.
Format:	Artigo de periódico biblioteca
Language:	Ingles English
Published:	2023-07-05
Subjects:	Biosensor, Screen-printed electrodes, Prussian blue, Non-invasive, Sustainable substrates,
Online Access:	http://www.alice.cnptia.embrapa.br/alice/handle/doc/1154806
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