Linkage disequilibrium and haplotype block structure in a composite beef cattle breed.

Linkage disequilibrium and haplotype block structure in a composite beef cattle breed.

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he development of linkage disequilibrium (LD) maps and the characterization of haplotype block structure at the population level are useful parameters for guiding genome wide association (GWA) studies, and for understanding the nature of non-linear association between phenotypes and genes. The elucidation of haplotype block structure can reduce the information of several single nucleotide polymorphisms (SNP) into the information of a haplotype block, reducing the number of SNPs in a coherent way for consideration in GWA and genomic selection studies.

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Main Authors: MOKRY, F. B., BUZANSKAS, M. E., MUDADU, M. de A., GROSSI, D. do A., HIGA, R. H., VENTURA, R. V., LIMA, A. O. de, SARGOLZAEI, M., MEIRELLES, S. L. C., SCHENKEL, F. S., SILVA, M. V. G. B., NICIURA, S. C. M., ALENCAR, M. M. de, MINARI, D. P., REGITANO, L. C. de A.
Other Authors: FABIANA BARICHELLO MOKRY, Federal University of São Carlos; MARCOS ELI BUZANSKAS, Universidade Estadual Paulista; MAURICIO DE ALVARENGA MUDADU, CPPSE; DANIELA DO AMARAL GROSSI, University of Guelph; ROBERTO HIROSHI HIGA, CNPTIA; RICARDO VIEIRA VENTURA, University of Guelph; ANDRESSA OLIVIERA DE LIMA, Federal University of São Carlos; MEHDI SARGOLZAEI, University of Guelph; SARAH LUGUNA CONCEIÇÃO MEIRELLES, Federal University of Lavras; FLÁVIO SCHRAMM SCHENKEL, University of Guelph; MARCOS VINICIUS GUALBERTO B SILVA, CNPGC; SIMONE CRISTINA MEO NICIURA, CPPSE; MAURICIO MELLO DE ALENCAR, CPPSE; DANÍSIO PRADO MUNARI, Universidade Estadual Paulista; LUCIANA CORREIA DE ALMEIDA REGITANO, CPPSE.
Format: Artigo de periódico biblioteca
Language:Ingles
English
Published: 2014-12-17
Subjects:Halplotype block, Linjage disequilibirium, Composite, beef cattle,
Online Access:http://www.alice.cnptia.embrapa.br/alice/handle/doc/1002985
http://www.biomedcentral.com/1471-2164/15/S7/S6
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http://www.alice.cnptia.embrapa.br/alice/handle/doc/1002985
http://www.biomedcentral.com/1471-2164/15/S7/S6

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