Pathogenesis and Treatment of Diabetes Mellitus [electronic resource] /

In this book on diabetes mellitus both the pathogenesis and treat­ ment of the disease will be discussed. Pathogenetic studies have led to the distinction between type I and type II diabetes. In type I hyperglycaemia is due predominantly to insulin deficiency; in type II insulin resistance is more important. Three pathogenetic factors are thought to play a role in the etiol­ ogy of type I diabetes: heredity, viral infections and immunity. There may be a relationship between these three aspects since genetic pre­ disposition changes the susceptibility to viral infections and/or the immunological defence against these infections. Insulitis ensues. Auto­ immune processes initiated by this chain of events may contribute to the destruction of the B cells in the islets of Langerhans and diabetes -may eventually follow. This means that at the time of the sudden out­ break of the disease, the destructive process has already been active for years.

Bibliographic Details

Main Authors:	Radder, J. K. editor., Lemkes, H. H. P. J. editor., Krans, H. M. J. editor., SpringerLink (Online service)
Format:	Texto biblioteca
Language:	eng
Published:	Dordrecht : Springer Netherlands, 1986
Subjects:	Medicine., Internal medicine., Diabetes., Medicine & Public Health., Internal Medicine.,
Online Access:	http://dx.doi.org/10.1007/978-94-009-4301-8
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