Sphingolipid Biochemistry [electronic resource] /

1 Chemistry of Glycosphingolipids -- 1.1. Introduction -- 1.2. Isolation of Glycosphingolipids -- 1.3. Characterization of Glycosphingolipids -- 1.4. Structure of Glycosphingolipids -- 1.5. Chemical Synthesis and Modification of Sphingosines and Glycosphingolipids -- 1.6. Pioneers in Glycolipid Chemistry -- 1.7. References -- 2 Sphingolipid Metabolism -- 2.1. Sphingosine Bases -- 2.2. The Psychosines -- 2.3. Ceramide (N-Acylsphingosine) -- 2.4. Galactosylceramide -- 2.5. Ceramide-galactoside-3-sulfate (Sulfatide) -- 2.6. Glucosylceramide -- 2.7. Ganglioside Metabolism -- 2.8. Sphingomyelin -- 2.9. Biosynthesis of the Sphingolipids: Summary -- 3 The Sphingolipidoses -- 3.1. Farber’s Lipogranulomatosis -- 3.2. Krabbe’s Disease (Globoid Cell Leukodystrophy) -- 3.3. Metachromatic Leukodystrophy -- 3.4. Gaucher’s Disease -- 3.5. Fabry’s Disease (Angiokeratoma Corporis Diffusium) -- 3.6. The Gangliosidoses -- 3.7. Niemann-Pick’s Disease -- 3.8. GM3 Gangliosidosis -- 3.9. General Comments -- 3.10. References -- 4 Glycosphingolipids in Cellular Interaction, Differentiation, and Oncogenesis -- 4.1. Introduction -- 4.2. Organization and Dynamic State of Glycohpids in Membranes -- 4.3. Glycolipids in Cellular Interaction and Differentiation -- 4.4. Role of Glycolipids in Cell Growth Control -- 4.5. Glycolipid Changes in Oncogenic Transformation: Deficiency in Glycolipid Function -- 4.6. Glycolipids as Possible Mediators of Immune Response -- 4.7. Postscript: Enigmas Concerning Glycohpid Functions -- 4.8. References -- 5 Glycolipid Antigens and Genetic Markers -- 5.1. Introduction -- 5.2. General Properties of Glycolipid Antigens -- 5.3. Heterophil Antigens -- 5.4. Glycolipids with Blood Group AB H Specificities -- 5.5. Glycolipids with Blood Group Lewis (Lea, Leb, Lec and Led) Specificities -- 5.6. Glycolipids with Blood Group P, P1, and Pk Specificities -- 5.7. Glycolipids with Blood Group I and i Specificities -- 5.8. Glycolipids with Blood Group J-Antigen Specificity -- 5.9. Tissue-Specific and Tumor-Associated Glycolipid Antigens -- 5.10. Modification of Blood Group Antigens -- 5.11. Tissue-Specific or Organ-Specific Glycolipid Antigens -- 5.12. Glycolipid Antigens Associated with Autoimmune Processes -- 5.13. References -- 6 Glycosphingolipids as Receptors -- 6.1. Gangliosides and the Serotonin Receptor -- 6.2. Gangliosides and Acetylcholine -- 6.3. Gangliosides and Interferon -- 6.4. Gangliosides and Bacterial Toxins -- 6.5. Gangliosides and Lymphocyte Markers -- 6.6. Gangliosides and Glycoprotein Hormone Receptors -- 6.7. Conclusions -- 6.8. References.

Bibliographic Details

Main Authors:	Kanfer, Julian N. author., Hakomori, Sen-itiroh. author., SpringerLink (Online service)
Format:	Texto biblioteca
Language:	eng
Published:	Boston, MA : Springer US, 1983
Subjects:	Life sciences., Lipids., Life Sciences., Lipidology.,
Online Access:	http://dx.doi.org/10.1007/978-1-4757-0396-2
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