Tuberculosis in children a perspective from life history theory
The early human life stages are considered of critical importance for human growth and maintenance, which are conditioned through molecular, physiological, and environmental constraints. During these periods, infections and undernutrition are major risk factors for reduction in growth velocity. Tuberculosis (TB), a human infectious disease, remains a significant source of morbidity and mortality among children in resource-limited settings and has been associated with TB susceptibility and disease progression. Undernutrition and weak immune system are considered to be the major risk factors to develop TB during the early years of human growth and development. From a life-history theory (LHT) perspective, modulation of physical growth takes place in response to nutrition and pathogens. In this chapter, we first review some hypotheses to describe and explain how an individual allocates energy to the body’s function and the resultant trade-offs that bind traits into growth and maintenance (immune function). We then theoretically explore and discuss the relation between growth, nutrition and TB from LHT perspective, using population-based studies carried out in Latin American (LA) countries.
| Main Authors: | , , |
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| Format: | Texto biblioteca |
| Language: | eng |
| Subjects: | Tuberculosis pulmonar, Nutrición infantil, Salud infantil, Teoría de la historia de vida, |
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