7 - methylxanthine is not involved in caffeine catabolism in Coffea dewevrei
To investigate the role of 7-methylxanthine as an intermediary compound in the degradation of theobromine to xanthine in coffee, leaves and immature fruits of Coffea dewevrei were incubated with [8 exponent -3 H] caffeine plus allopurinol. In vivo inhibition of xanthine degradation occurred in fruits and leaves fed with allopurinol since marked incorporation of radioactivity in xanthine and 3-methylxanthine was observed. Nevertheless, HPLC analysis did not reveal any radioactivity in 7-methylxanthine. The results suggest that in coffee theobromine is degraded to xanthine via 3-methylxanthine and 7-methylxanthine is exclusively involved in the caffeine biosynthesis pathway.
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| Format: | biblioteca |
| Published: |
1993
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| Subjects: | COFFEA DEWEVREI, CAFEINA, XANTINAS, TEOBROMINA, ALCALOIDES DE LA XANTINA, CATABOLISMO, |
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