Heat-Inactivated Akkermansia muciniphila Improves Gut Permeability but Does Not Prevent Development of Non-Alcoholic Steatohepatitis in Diet-Induced Obese Ldlr−/−.Leiden Mice

by Morrison, Martine C., Gart, Eveline, van Duyvenvoorde, Wim, Snabel, Jessica, Nielsen, Mette Juul, Leeming, Diana Julie, Menke, Aswin, Kleemann, Robert

Replacement of dietary saturated fat by PUFA-rich pumpkin seed oil attenuates non-alcoholic fatty liver disease and atherosclerosis development, with additional health effects of v...

by Morrison, M.C., Mulder, Petra, Stavro, P.M., Suárez, Manuel, Arola-Arnal, Anna, Van Duyvenvoorde, Wim, Kooistra, Teake, Wielinga, P.Y., Kleemann, Robert

Intervention with isoleucine or valine corrects hyperinsulinemia and reduces intrahepatic diacylglycerols, liver steatosis, and inflammation in Ldlr−/−.Leiden mice with manifest ob...

by Gart, Eveline, van Duyvenvoorde, Wim, Caspers, Martien P.M., van Trigt, Nikki, Snabel, Jessica, Menke, Aswin, Keijer, Jaap, Salic, Kanita, Morrison, Martine C., Kleemann, Robert

Combined Treatment with L-Carnitine and Nicotinamide Riboside Improves Hepatic Metabolism and Attenuates Obesity and Liver Steatosis

by Salic, Kanita, Gart, Eveline, Seidel, Florine, Verschuren, Lars, Caspers, Martien, van Duyvenvoorde, Wim, Wong, Kari E., Keijer, Jaap, Bobeldijk-Pastorova, Ivana, Wielinga, Peter Y., Kleemann, Robert

Cholesterol Accumulation as a Driver of Hepatic Inflammation Under Translational Dietary Conditions Can Be Attenuated by a Multicomponent Medicine

by Mueller, Andrea M., Kleemann, Robert, Gart, Eveline, van Duyvenvoorde, Wim, Verschuren, Lars, Caspers, Martien, Menke, Aswin, Krömmelbein, Natascha, Salic, Kanita, Burmeister, Yvonne, Seilheimer, Bernd, Morrison, Martine C.

Krill oil treatment increases distinct pufas and oxylipins in adipose tissue and liver and attenuates obesity-associated inflammation via direct and indirect mechanisms

by Gart, Eveline, Salic, Kanita, Morrison, Martine C., Caspers, Martien, van Duyvenvoorde, Wim, Heijnk, Marieke, Giera, Martin, Bobeldijk-Pastorova, Ivana, Keijer, Jaap, Storsve, Andreas B., Hals, Petter Arnt, Kleemann, Robert

Metabolic dysfunction-associated steatotic liver disease is associated with effects on cerebral perfusion and white matter integrity

by Seidel, Florine, Vreeken, Debby, Custers, Emma, Wiesmann, Maximilian, Özsezen, Serdar, van Duyvenvoorde, Wim, Caspers, Martien, Menke, Aswin, Morrison, Martine C., Verschuren, Lars, Duering, Marco, Hazebroek, Eric J., Kiliaan, Amanda J., Kleemann, Robert

Propionic acid and not caproic acid, attenuates nonalcoholic steatohepatitis and improves (cerebro) vascular functions in obese Ldlr−/−.Leiden mice

by Tengeler, Anouk C., Gart, Eveline, Wiesmann, Maximilian, Arnoldussen, Ilse A.C., van Duyvenvoorde, Wim, Hoogstad, Marloes, Dederen, Pieter J., Verweij, Vivienne, Geenen, Bram, Kozicz, Tamas, Kleemann, Robert, Morrison, Martine C., Kiliaan, Amanda J.

Butyrate Protects against Diet-Induced NASH and Liver Fibrosis and Suppresses Specific Non-Canonical TGF-β Signaling Pathways in Human Hepatic Stellate Cells

by Gart, Eveline, van Duyvenvoorde, Wim, Toet, Karin, Caspers, Martien P.M., Verschuren, Lars, Nielsen, Mette Juul, Leeming, Diana Julie, Lima, Everton Souto, Menke, Aswin, Hanemaaijer, Roeland, Keijer, Jaap, Salic, Kanita, Kleemann, Robert, Morrison, Martine C.

Translational characterization of the temporal dynamics of metabolic dysfunctions in liver, adipose tissue and the gut during diet-induced NASH development in Ldlr−/−.Leiden mice...

by Gart, Eveline, van Duyvenvoorde, Wim, Snabel, Jessica M., de Ruiter, Christa, Attema, Joline, Caspers, Martien P.M., Lek, Serene, van Heuven, Bertie Joan, Speksnijder, Arjen G.C.L., Giera, Martin, Menke, Aswin, Salic, Kanita, Bence, Kendra K., Tesz, Gregory J., Keijer, Jaap, Kleemann, Robert, Morrison, Martine C.