6′-Benzyloxy-4-bromo-2′-hydroxychalcone is cytotoxic against human leukaemia cells and induces caspase-8- and reactive oxygen species-dependent apoptosis

by Saavedra, Ester, Del Rosario, Henoc, Brouard, Ignacio, Quintana, José, Estévez, Francisco
Published 2019-01-25

The synthetic flavanone 6-methoxy-2-(naphthalen-1-yl)chroman-4-one induces apoptosis and activation of the MAPK pathway in human U-937 leukaemia cells

by Saavedra, Ester, Del Rosario, Henoc, Brouard, Ignacio, Hernández-Garcés, Judith, García, Celina, Quintana, José, Estévez, Francisco
Published 2020-01-01

Chlorinated Guaiane-Type Sesquiterpene Lactones as Cytotoxic Agents against Human Tumor Cells

by Estévez-Sarmiento, Francisco, Saavedra, Ester, Ruiz-Estévez, Mercedes, León, Francisco, Quintana, José, Brouard, Ignacio, Estévez, Francisco
Published 2020-12-21

Guanidine derivatives containing the chalcone skeleton are potent antiproliferative compounds against human leukemia cells

by Estévez, Francisco, Saavedra, Ester, Brouard, Ignacio, Peyrac, Jesús, Hernández-Garcés, Judith, García, Celina, Quintana, José, Estévez, Francisco
Published 2022

Structure-activity relationships reveal a 2-furoyloxychalcone as a potent cytotoxic and apoptosis inducer for human U-937 and HL-60 leukaemia cells

by Rosario, Henoc del, Saavedra, Ester, Brouard, Ignacio, González-Santana, Daniel, García Cortés, Celia, Spínola-Lasso, Elena, Tabraue, Carlos, Quintana, José, Estévez, Francisco
Published 2022-10