Generation of in vitro data to model dose dependent in vivo DNA binding of genotoxic carcinogens and its consequences: the case of estragole

by Paini, A.

Use of physiologically based biokinetic (PBBK) modeling to study estragole bioactivation and detoxification in huyman as compared to male rat

by Punt, A., Paini, A., Freidig, A.P., Delatour, T., Scholz, G., Schilter, B., van Bladeren, P.J., Rietjens, I.

Next generation physiologically based kinetic (NG-PBK) models in support of regulatory decision making

by Paini, A., Leonard, J.A., Joossens, E., Bessems, J.G.M., Desalegn, A., Dorne, J.L., Gosling, J.P., Heringa, M.B., Klaric, M., Kliment, T., Kramer, N.I., Loizou, G., Louisse, J., Lumen, A., Madden, J.C., Patterson, E.A., Proença, S., Punt, A., Setzer, R.W., Suciu, N., Troutman, J., Yoon, M., Worth, A., Tan, Y.M.