New approach methodologies : A quantitative in vitro to in vivo extrapolation case study with PFASs

by Fragki, Styliani, Louisse, Jochem, Bokkers, Bas, Luijten, Mirjam, Peijnenburg, Ad, Rijkers, Deborah, Piersma, Aldert H., Zeilmaker, Marco J.

Determination of in vitro hepatotoxic potencies of a series of perfluoroalkyl substances (PFASs) based on gene expression changes in HepaRG liver cells

by Louisse, Jochem, Fragki, Styliani, Rijkers, Deborah, Janssen, Aafke, van Dijk, Bas, Leenders, Liz, Staats, Martijn, Bokkers, Bas, Zeilmaker, Marco, Piersma, Aldert, Luijten, Mirjam, Hoogenboom, Ron, Peijnenburg, Ad

EFSA Project on the use of NAMs to explore the immunotoxicity of PFAS

by Corsini, Emanuela, Iulini, Martina, Galbiati, Valentina, Maddalon, Ambra, Pappalardo, Francesco, Russo, Giulia, Hoogenboom, Ron L.A.P., Beekmann, Karsten, Janssen, Aafke W.F., Louisse, Jochem, Fragki, Styliani, Paini, Alicia

Systemic PFOS and PFOA exposure and disturbed lipid homeostasis in humans: what do we know and what not?

by Fragki, Styliani S., Dirven, Hubert, Fletcher, Tony, Grasl-Kraupp, Bettina, Bjerve Gützkow, Kristine, Hoogenboom, Ron, Kersten, Sander, Lindeman, Birgitte, Louisse, Jochem, Peijnenburg, Ad, Piersma, Aldert H., Princen, Hans M.G., Uhl, Maria, Westerhout, Joost, Zeilmaker, Marco J., Luijten, Mirjam

Systemic PFOS and PFOA exposure and disturbed lipid homeostasis in humans : what do we know and what not?

by Fragki, Styliani S., Dirven, Hubert, Fletcher, Tony, Grasl-Kraupp, Bettina, Bjerve Gützkow, Kristine, Hoogenboom, Ron, Kersten, Sander, Lindeman, Birgitte, Louisse, Jochem, Peijnenburg, Ad, Piersma, Aldert H., Princen, Hans M.G., Uhl, Maria, Westerhout, Joost, Zeilmaker, Marco J., Luijten, Mirjam

Towards best use and regulatory acceptance of generic physiologically based kinetic (PBK) models for in vitro-to-in vivo extrapolation (IVIVE) in chemical risk assessment

by Najjar, Abdulkarim, Punt, Ans, Wambaugh, John, Paini, Alicia, Ellison, Corie, Fragki, Styliani, Bianchi, Enrica, Zhang, Fagen, Westerhout, Joost, Mueller, Dennis, Li, Hequn, Shi, Quan, Gant, Timothy W., Botham, Phil, Bars, Rémi, Piersma, Aldert, van Ravenzwaay, Ben, Kramer, Nynke I.