Hepatic overexpression of cAMP-responsive element modulator α induces a regulatory T-cell response in a murine model of chronic liver disease

by Kuttkat, Nadine, Mohs, Antje, Ohl, Kim, Hooiveld, Guido, Longerich, Thomas, Tenbrock, Klaus, Cubero, Francisco Javier, Trautwein, Christian

Dual function of Jnk1 and Jnk2 in hepatocytes is essential to protect against toxic liver injury

by Zhao, Gang, Cubero, Francisco J., Nevzorova, Yulia A., Boekschoten, Mark, Peng, Jin, Hatting, M., Muller, Michael, Roskams, T., Trautwein, Christian

Jnk1 in murine hepatic stellate cells is a crucial mediator of liver fibrogenesis

by Zhao, Gang, Hatting, Maximilian, Nevzorova, Yulia A., Boekschoten, Mark, Drvarov, Oliver, Roskams, Tania, Muller, Michael, Cubero, Francisco, Trautwein, Christian

TNFR1 controls apoptosis and chronic liver disease in hepatocyte-specific IKKγ (Nemo) mice.

by Singh, Anjana, Cubero, Francisco J., Borkham-Kamphorst, Erawan, Nevzorova, Yulia A., Al Masaoudi, Malika, Boekschoten, Mark, Gassler, Nikolaus, Weiskirchen, Ralf, Luedde, Tom, Heikenwalder, Mathias, Muller, Michael, Liedtke, Christian, Trautwein, Christian

JNKs protect from cholestatic liver disease progression by modulating Apelin signalling

by Mohamed, Mohamed Ramadan, Haybaeck, Johannes, Wu, Hanghang, Su, Huan, Bartneck, Matthias, Lin, Cheng, Boekschoten, Mark V., Boor, Peter, Goeppert, Benjamin, Rupp, Christian, Strnad, Pavel, Davis, Roger J., Cubero, Francisco Javier, Trautwein, Christian

Hepatocytic c-Jun N-terminal kinases (JNK)-1/2 function determines cell fate during carcinogenesis

by Cubero, Francisco Javier, Mohamed, Mohamed Ramadan, Woitok, Marius M., Zhao, Gang, Hatting, Maximilian, Nevzorova, Yulia A., Chen, Chaobo, Haybaeck, Johannes, de Bruin, Alain, Avila, Matias A., Boekschoten, Mark, Davis, Roger J., Trautwein, Christian

Inhibition of ALK3-mediated signalling pathway protects against acetaminophen-induced liver injury

by Marañón, Patricia, Rey, Esther, Isaza, Stephania C., Wu, Hanghang, Rada, Patricia, Choya-Foces, Carmen, Martínez-Ruiz, Antonio, Martín, M. Ángeles, Ramos, Sonia, García-Monzón, Carmelo, Cubero, Francisco Javier, Valverde, Ángela M., González-Rodríguez, Águeda
Published 2024

Loss of c‐Jun N‐terminal Kinase 1 and 2 Function in Liver Epithelial Cells Triggers Biliary Hyperproliferation Resembling Cholangiocarcinoma

by Cubero, Francisco Javier, Mohamed, Mohamed Ramadan, Woitok, Marius M., Zhao, Gang, Hatting, Maximilian, Nevzorova, Yulia A., Chen, Chaobo, Haybaeck, Johannes, de Bruin, Alain, Avila, Matias A., Boekschoten, Mark V., Davis, Roger J., Trautwein, Christian

Hematopoietic cells-derived Jnk1 is crucial for chronic inflammation and carcinogenesis in an experimental model of liver injury

by Cubero, Francisco J., Zhao, Gang, Nevzorova, Yulia A., Hatting, Maximilian, Al Masaoudi, Malika, Verdier, Julien, Peng, Jin, Schaefer, Frederik M., Hermanns, Nadine, Boekschoten, Mark, Grouls, Christoph, Gassler, Nikolaus, Kiessling, Fabian, Muller, Michael, Davis, Roger J., Liedtke, Christian, Trautwein, Christian