“Maxillary lateral incisor partial anodontia sequence”: a clinical entity with epigenetic origin

ABSTRACT The relationship between maxillary lateral incisor anodontia and the palatal displacement of unerupted maxillary canines cannot be considered as a multiple tooth abnormality with defined genetic etiology in order to be regarded as a “syndrome”. Neither were the involved genes identified and located in the human genome, nor was it presumed on which chromosome the responsible gene would be located. The palatal maxillary canine displacement in cases of partial anodontia of the maxillary lateral incisor is potentially associated with environmental changes caused by its absence in its place of formation and eruption, which would characterize an epigenetic etiology. The lack of the maxillary lateral incisor in the canine region means removing one of the reference guides for the eruptive trajectory of the maxillary canine, which would therefore, not erupt and /or impact on the palate. Consequently, and in sequence, it would lead to malocclusion, maxillary atresia, transposition, prolonged retention of the deciduous canine and resorption in the neighboring teeth. Thus, we can say that we are dealing with a set of anomalies and multiple sequential changes known as sequential development anomalies or, simply, sequence. Once the epigenetics and sequential condition is accepted for this clinical picture, it could be called “Maxillary Lateral Incisor Partial Anodontia Sequence.”

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Main Authors: Consolaro,Alberto, Cardoso,Maurício Almeida, Consolaro,Renata Bianco
Format: Digital revista
Language:English
Published: Dental Press International 2017
Online Access:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S2176-94512017000600028
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spelling oai:scielo:S2176-945120170006000282019-07-26“Maxillary lateral incisor partial anodontia sequence”: a clinical entity with epigenetic originConsolaro,AlbertoCardoso,Maurício AlmeidaConsolaro,Renata Bianco Partial anodontia Conical teeth Impacted canines Unerupted teeth ABSTRACT The relationship between maxillary lateral incisor anodontia and the palatal displacement of unerupted maxillary canines cannot be considered as a multiple tooth abnormality with defined genetic etiology in order to be regarded as a “syndrome”. Neither were the involved genes identified and located in the human genome, nor was it presumed on which chromosome the responsible gene would be located. The palatal maxillary canine displacement in cases of partial anodontia of the maxillary lateral incisor is potentially associated with environmental changes caused by its absence in its place of formation and eruption, which would characterize an epigenetic etiology. The lack of the maxillary lateral incisor in the canine region means removing one of the reference guides for the eruptive trajectory of the maxillary canine, which would therefore, not erupt and /or impact on the palate. Consequently, and in sequence, it would lead to malocclusion, maxillary atresia, transposition, prolonged retention of the deciduous canine and resorption in the neighboring teeth. Thus, we can say that we are dealing with a set of anomalies and multiple sequential changes known as sequential development anomalies or, simply, sequence. Once the epigenetics and sequential condition is accepted for this clinical picture, it could be called “Maxillary Lateral Incisor Partial Anodontia Sequence.”info:eu-repo/semantics/openAccessDental Press InternationalDental Press Journal of Orthodontics v.22 n.6 20172017-11-01info:eu-repo/semantics/articletext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S2176-94512017000600028en10.1590/2177-6709.22.6.028-034.oin
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country Brasil
countrycode BR
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region America del Sur
libraryname SciELO
language English
format Digital
author Consolaro,Alberto
Cardoso,Maurício Almeida
Consolaro,Renata Bianco
spellingShingle Consolaro,Alberto
Cardoso,Maurício Almeida
Consolaro,Renata Bianco
“Maxillary lateral incisor partial anodontia sequence”: a clinical entity with epigenetic origin
author_facet Consolaro,Alberto
Cardoso,Maurício Almeida
Consolaro,Renata Bianco
author_sort Consolaro,Alberto
title “Maxillary lateral incisor partial anodontia sequence”: a clinical entity with epigenetic origin
title_short “Maxillary lateral incisor partial anodontia sequence”: a clinical entity with epigenetic origin
title_full “Maxillary lateral incisor partial anodontia sequence”: a clinical entity with epigenetic origin
title_fullStr “Maxillary lateral incisor partial anodontia sequence”: a clinical entity with epigenetic origin
title_full_unstemmed “Maxillary lateral incisor partial anodontia sequence”: a clinical entity with epigenetic origin
title_sort “maxillary lateral incisor partial anodontia sequence”: a clinical entity with epigenetic origin
description ABSTRACT The relationship between maxillary lateral incisor anodontia and the palatal displacement of unerupted maxillary canines cannot be considered as a multiple tooth abnormality with defined genetic etiology in order to be regarded as a “syndrome”. Neither were the involved genes identified and located in the human genome, nor was it presumed on which chromosome the responsible gene would be located. The palatal maxillary canine displacement in cases of partial anodontia of the maxillary lateral incisor is potentially associated with environmental changes caused by its absence in its place of formation and eruption, which would characterize an epigenetic etiology. The lack of the maxillary lateral incisor in the canine region means removing one of the reference guides for the eruptive trajectory of the maxillary canine, which would therefore, not erupt and /or impact on the palate. Consequently, and in sequence, it would lead to malocclusion, maxillary atresia, transposition, prolonged retention of the deciduous canine and resorption in the neighboring teeth. Thus, we can say that we are dealing with a set of anomalies and multiple sequential changes known as sequential development anomalies or, simply, sequence. Once the epigenetics and sequential condition is accepted for this clinical picture, it could be called “Maxillary Lateral Incisor Partial Anodontia Sequence.”
publisher Dental Press International
publishDate 2017
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S2176-94512017000600028
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