Phytoconstituents from Sidastrum micranthum (A. St.-Hil.) Fryxell (Malvaceae) and antimicrobial activity of pheophytin a
abstract Sidastrum micranthum (A. St.-Hil.) Fryxell, a member of the Malvaceae family, is called malva preta in Brazil. As this species is commonly used to treat bronchitis, cough, and asthma, better knowledge of its chemical compounds is important. The phytochemical study of its hexane extract, using chromatographic techniques, led to isolation of six compounds: the triterpene isoarborinol, a mixture of sitosterol and stigmasterol, sitosterol-3-O-β-D-glucopyranoside, pheophytin a, and 132-hydroxy-(132-S)-pheophytin a. Structural identification of these compounds was carried out using spectroscopic methods such as IR and 1D and 2D NMR (HOMOCOSY, HMQC, HMBC, and NOESY). Compounds isolated from S. micranthum were screened for their in vitro antifungal and antibacterial activity against twenty fungal and bacterial standard strains. Pheophytin a exhibited antimicrobial action against all microorganisms tested.
Main Authors: | , , , , , , |
---|---|
Format: | Digital revista |
Language: | English |
Published: |
Universidade de São Paulo, Faculdade de Ciências Farmacêuticas
2015
|
Online Access: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502015000400861 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
id |
oai:scielo:S1984-82502015000400861 |
---|---|
record_format |
ojs |
spelling |
oai:scielo:S1984-825020150004008612016-03-30Phytoconstituents from Sidastrum micranthum (A. St.-Hil.) Fryxell (Malvaceae) and antimicrobial activity of pheophytin aGomes,Roosevelt AlbuquerqueTeles,Yanna Carolina FerreiraPereira,Fillipe de OliveiraRodrigues,Luis Alberto de SousaLima,Edeltrudes de OliveiraAgra,Maria de FátimaSouza,Maria de Fátima Vanderlei de Malvaceae/phytochemistry Sidastrum micranthum/phytochemistry Sidastrum micranthum/antimicrobial activity/in vitro study Pheophytins Medicinal plants. abstract Sidastrum micranthum (A. St.-Hil.) Fryxell, a member of the Malvaceae family, is called malva preta in Brazil. As this species is commonly used to treat bronchitis, cough, and asthma, better knowledge of its chemical compounds is important. The phytochemical study of its hexane extract, using chromatographic techniques, led to isolation of six compounds: the triterpene isoarborinol, a mixture of sitosterol and stigmasterol, sitosterol-3-O-β-D-glucopyranoside, pheophytin a, and 132-hydroxy-(132-S)-pheophytin a. Structural identification of these compounds was carried out using spectroscopic methods such as IR and 1D and 2D NMR (HOMOCOSY, HMQC, HMBC, and NOESY). Compounds isolated from S. micranthum were screened for their in vitro antifungal and antibacterial activity against twenty fungal and bacterial standard strains. Pheophytin a exhibited antimicrobial action against all microorganisms tested.info:eu-repo/semantics/openAccessUniversidade de São Paulo, Faculdade de Ciências FarmacêuticasBrazilian Journal of Pharmaceutical Sciences v.51 n.4 20152015-12-01info:eu-repo/semantics/articletext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502015000400861en10.1590/S1984-82502015000400012 |
institution |
SCIELO |
collection |
OJS |
country |
Brasil |
countrycode |
BR |
component |
Revista |
access |
En linea |
databasecode |
rev-scielo-br |
tag |
revista |
region |
America del Sur |
libraryname |
SciELO |
language |
English |
format |
Digital |
author |
Gomes,Roosevelt Albuquerque Teles,Yanna Carolina Ferreira Pereira,Fillipe de Oliveira Rodrigues,Luis Alberto de Sousa Lima,Edeltrudes de Oliveira Agra,Maria de Fátima Souza,Maria de Fátima Vanderlei de |
spellingShingle |
Gomes,Roosevelt Albuquerque Teles,Yanna Carolina Ferreira Pereira,Fillipe de Oliveira Rodrigues,Luis Alberto de Sousa Lima,Edeltrudes de Oliveira Agra,Maria de Fátima Souza,Maria de Fátima Vanderlei de Phytoconstituents from Sidastrum micranthum (A. St.-Hil.) Fryxell (Malvaceae) and antimicrobial activity of pheophytin a |
author_facet |
Gomes,Roosevelt Albuquerque Teles,Yanna Carolina Ferreira Pereira,Fillipe de Oliveira Rodrigues,Luis Alberto de Sousa Lima,Edeltrudes de Oliveira Agra,Maria de Fátima Souza,Maria de Fátima Vanderlei de |
author_sort |
Gomes,Roosevelt Albuquerque |
title |
Phytoconstituents from Sidastrum micranthum (A. St.-Hil.) Fryxell (Malvaceae) and antimicrobial activity of pheophytin a |
title_short |
Phytoconstituents from Sidastrum micranthum (A. St.-Hil.) Fryxell (Malvaceae) and antimicrobial activity of pheophytin a |
title_full |
Phytoconstituents from Sidastrum micranthum (A. St.-Hil.) Fryxell (Malvaceae) and antimicrobial activity of pheophytin a |
title_fullStr |
Phytoconstituents from Sidastrum micranthum (A. St.-Hil.) Fryxell (Malvaceae) and antimicrobial activity of pheophytin a |
title_full_unstemmed |
Phytoconstituents from Sidastrum micranthum (A. St.-Hil.) Fryxell (Malvaceae) and antimicrobial activity of pheophytin a |
title_sort |
phytoconstituents from sidastrum micranthum (a. st.-hil.) fryxell (malvaceae) and antimicrobial activity of pheophytin a |
description |
abstract Sidastrum micranthum (A. St.-Hil.) Fryxell, a member of the Malvaceae family, is called malva preta in Brazil. As this species is commonly used to treat bronchitis, cough, and asthma, better knowledge of its chemical compounds is important. The phytochemical study of its hexane extract, using chromatographic techniques, led to isolation of six compounds: the triterpene isoarborinol, a mixture of sitosterol and stigmasterol, sitosterol-3-O-β-D-glucopyranoside, pheophytin a, and 132-hydroxy-(132-S)-pheophytin a. Structural identification of these compounds was carried out using spectroscopic methods such as IR and 1D and 2D NMR (HOMOCOSY, HMQC, HMBC, and NOESY). Compounds isolated from S. micranthum were screened for their in vitro antifungal and antibacterial activity against twenty fungal and bacterial standard strains. Pheophytin a exhibited antimicrobial action against all microorganisms tested. |
publisher |
Universidade de São Paulo, Faculdade de Ciências Farmacêuticas |
publishDate |
2015 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502015000400861 |
work_keys_str_mv |
AT gomesrooseveltalbuquerque phytoconstituentsfromsidastrummicranthumasthilfryxellmalvaceaeandantimicrobialactivityofpheophytina AT telesyannacarolinaferreira phytoconstituentsfromsidastrummicranthumasthilfryxellmalvaceaeandantimicrobialactivityofpheophytina AT pereirafillipedeoliveira phytoconstituentsfromsidastrummicranthumasthilfryxellmalvaceaeandantimicrobialactivityofpheophytina AT rodriguesluisalbertodesousa phytoconstituentsfromsidastrummicranthumasthilfryxellmalvaceaeandantimicrobialactivityofpheophytina AT limaedeltrudesdeoliveira phytoconstituentsfromsidastrummicranthumasthilfryxellmalvaceaeandantimicrobialactivityofpheophytina AT agramariadefatima phytoconstituentsfromsidastrummicranthumasthilfryxellmalvaceaeandantimicrobialactivityofpheophytina AT souzamariadefatimavanderleide phytoconstituentsfromsidastrummicranthumasthilfryxellmalvaceaeandantimicrobialactivityofpheophytina |
_version_ |
1756437797016698880 |