Synergy: an old wisdom, a new paradigm for pharmacotherapy

Synergy: an old wisdom, a new paradigm for pharmacotherapy

Synergy is one of the governing principles of the natural world, and is one of the reasons for the increasing complexity of the evolutionary process. Broadly speaking, it relates to the cooperative effects produced by the interaction between various forces, elements, parts or individuals in a given context. Since the last century, some clinical studies have described the increased efficiency of a combination of drugs. To study the effects of the drug interactions, the most commonly cited model is that of Loewe, and the classical graphical representation is the iso-effect curve (isobologram). Plants contain an enormous diversity of specialized micromolecules, therefore there is a high likelihood of interactions between them. Through recent synergy studies, various synergistic interactions have been demonstrated among extracts of different plants, and between components of the same extract.

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Main Author: Biavatti,Maique Weber
Format: Digital revista
Language:English
Published: Universidade de São Paulo, Faculdade de Ciências Farmacêuticas 2009
Online Access:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502009000300002
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spelling oai:scielo:S1984-825020090003000022009-12-01Synergy: an old wisdom, a new paradigm for pharmacotherapyBiavatti,Maique Weber Natural extracts Synergy Phytotherapeutics Synergy is one of the governing principles of the natural world, and is one of the reasons for the increasing complexity of the evolutionary process. Broadly speaking, it relates to the cooperative effects produced by the interaction between various forces, elements, parts or individuals in a given context. Since the last century, some clinical studies have described the increased efficiency of a combination of drugs. To study the effects of the drug interactions, the most commonly cited model is that of Loewe, and the classical graphical representation is the iso-effect curve (isobologram). Plants contain an enormous diversity of specialized micromolecules, therefore there is a high likelihood of interactions between them. Through recent synergy studies, various synergistic interactions have been demonstrated among extracts of different plants, and between components of the same extract.info:eu-repo/semantics/openAccessUniversidade de São Paulo, Faculdade de Ciências FarmacêuticasBrazilian Journal of Pharmaceutical Sciences v.45 n.3 20092009-09-01info:eu-repo/semantics/articletext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502009000300002en10.1590/S1984-82502009000300002
institution SCIELO
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country Brasil
countrycode BR
component Revista
access En linea
databasecode rev-scielo-br
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region America del Sur
libraryname SciELO
language English
format Digital
author Biavatti,Maique Weber
spellingShingle Biavatti,Maique Weber
Synergy: an old wisdom, a new paradigm for pharmacotherapy
author_facet Biavatti,Maique Weber
author_sort Biavatti,Maique Weber
title Synergy: an old wisdom, a new paradigm for pharmacotherapy
title_short Synergy: an old wisdom, a new paradigm for pharmacotherapy
title_full Synergy: an old wisdom, a new paradigm for pharmacotherapy
title_fullStr Synergy: an old wisdom, a new paradigm for pharmacotherapy
title_full_unstemmed Synergy: an old wisdom, a new paradigm for pharmacotherapy
title_sort synergy: an old wisdom, a new paradigm for pharmacotherapy
description Synergy is one of the governing principles of the natural world, and is one of the reasons for the increasing complexity of the evolutionary process. Broadly speaking, it relates to the cooperative effects produced by the interaction between various forces, elements, parts or individuals in a given context. Since the last century, some clinical studies have described the increased efficiency of a combination of drugs. To study the effects of the drug interactions, the most commonly cited model is that of Loewe, and the classical graphical representation is the iso-effect curve (isobologram). Plants contain an enormous diversity of specialized micromolecules, therefore there is a high likelihood of interactions between them. Through recent synergy studies, various synergistic interactions have been demonstrated among extracts of different plants, and between components of the same extract.
publisher Universidade de São Paulo, Faculdade de Ciências Farmacêuticas
publishDate 2009
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502009000300002
work_keys_str_mv AT biavattimaiqueweber synergyanoldwisdomanewparadigmforpharmacotherapy
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