Basal ganglia calcification as a putative cause for cognitive decline

ABSTRACT Basal ganglia calcifications (BGC) may be present in various medical conditions, such as infections, metabolic, psychiatric and neurological diseases, associated with different etiologies and clinical outcomes, including parkinsonism, psychosis, mood swings and dementia. A literature review was performed highlighting the main neuropsychological findings of BGC, with particular attention to clinical reports of cognitive decline. Neuroimaging studies combined with neuropsychological analysis show that some patients have shown progressive disturbances of selective attention, declarative memory and verbal perseveration. Therefore, the calcification process might represent a putative cause for dementia syndromes, suggesting a probable link among calcinosis, the aging process and eventually with neuronal death. The increasing number of reports available will foster a necessary discussion about cerebral calcinosis and its role in determining symptomatology in dementia patients

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Main Authors: Oliveira,João Ricardo Mendes de, Oliveira,Matheus Fernandes de
Format: Digital revista
Language:English
Published: Academia Brasileira de Neurologia, Departamento de Neurologia Cognitiva e Envelhecimento 2013
Online Access:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1980-57642013000200151
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spelling oai:scielo:S1980-576420130002001512016-06-09Basal ganglia calcification as a putative cause for cognitive declineOliveira,João Ricardo Mendes deOliveira,Matheus Fernandes de basal ganglia dementia calcinosis ABSTRACT Basal ganglia calcifications (BGC) may be present in various medical conditions, such as infections, metabolic, psychiatric and neurological diseases, associated with different etiologies and clinical outcomes, including parkinsonism, psychosis, mood swings and dementia. A literature review was performed highlighting the main neuropsychological findings of BGC, with particular attention to clinical reports of cognitive decline. Neuroimaging studies combined with neuropsychological analysis show that some patients have shown progressive disturbances of selective attention, declarative memory and verbal perseveration. Therefore, the calcification process might represent a putative cause for dementia syndromes, suggesting a probable link among calcinosis, the aging process and eventually with neuronal death. The increasing number of reports available will foster a necessary discussion about cerebral calcinosis and its role in determining symptomatology in dementia patientsinfo:eu-repo/semantics/openAccessAcademia Brasileira de Neurologia, Departamento de Neurologia Cognitiva e EnvelhecimentoDementia & Neuropsychologia v.7 n.2 20132013-06-01info:eu-repo/semantics/articletext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1980-57642013000200151en10.1590/S1980-57642013DN70200003
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libraryname SciELO
language English
format Digital
author Oliveira,João Ricardo Mendes de
Oliveira,Matheus Fernandes de
spellingShingle Oliveira,João Ricardo Mendes de
Oliveira,Matheus Fernandes de
Basal ganglia calcification as a putative cause for cognitive decline
author_facet Oliveira,João Ricardo Mendes de
Oliveira,Matheus Fernandes de
author_sort Oliveira,João Ricardo Mendes de
title Basal ganglia calcification as a putative cause for cognitive decline
title_short Basal ganglia calcification as a putative cause for cognitive decline
title_full Basal ganglia calcification as a putative cause for cognitive decline
title_fullStr Basal ganglia calcification as a putative cause for cognitive decline
title_full_unstemmed Basal ganglia calcification as a putative cause for cognitive decline
title_sort basal ganglia calcification as a putative cause for cognitive decline
description ABSTRACT Basal ganglia calcifications (BGC) may be present in various medical conditions, such as infections, metabolic, psychiatric and neurological diseases, associated with different etiologies and clinical outcomes, including parkinsonism, psychosis, mood swings and dementia. A literature review was performed highlighting the main neuropsychological findings of BGC, with particular attention to clinical reports of cognitive decline. Neuroimaging studies combined with neuropsychological analysis show that some patients have shown progressive disturbances of selective attention, declarative memory and verbal perseveration. Therefore, the calcification process might represent a putative cause for dementia syndromes, suggesting a probable link among calcinosis, the aging process and eventually with neuronal death. The increasing number of reports available will foster a necessary discussion about cerebral calcinosis and its role in determining symptomatology in dementia patients
publisher Academia Brasileira de Neurologia, Departamento de Neurologia Cognitiva e Envelhecimento
publishDate 2013
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1980-57642013000200151
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AT oliveiramatheusfernandesde basalgangliacalcificationasaputativecauseforcognitivedecline
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