Cognitive impairment in multiple system atrophy: Changing concepts

Cognitive impairment in multiple system atrophy: Changing concepts

Abstract Multiple system atrophy (MSA) is characterized by a variable combination of cerebellar ataxia, parkinsonism and pyramidal signs associated with autonomic failure. Classically, cognitive impairment was not considered a clinical feature of MSA and dementia was pointed out as an exclusion diagnostic criteria. Based on comprehensive neuropsychological assessment, cognitive impairment was found to be a frequent feature in MSA, and clinically-defined dementia is now reported in 14-16% of cases. This article reviews the current data on cognitive impairment in MSA along with its neuropsychological profile and pathophysiology.

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Main Authors: Abrahão,Agessandro, Dutra,Livia Almeida, Braga Neto,Pedro, Pedroso,José Luiz, Oliveira,Ricardo Araújo de, Barsottini,Orlando Graziani Povoas
Format: Digital revista
Language:English
Published: Academia Brasileira de Neurologia, Departamento de Neurologia Cognitiva e Envelhecimento 2011
Online Access:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1980-57642011000400303
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spelling oai:scielo:S1980-576420110004003032016-07-19Cognitive impairment in multiple system atrophy: Changing conceptsAbrahão,AgessandroDutra,Livia AlmeidaBraga Neto,PedroPedroso,José LuizOliveira,Ricardo Araújo deBarsottini,Orlando Graziani Povoas multiple system atrophy cognitive impairment dementia atypical parkinsonism neuropsychological evaluation. Abstract Multiple system atrophy (MSA) is characterized by a variable combination of cerebellar ataxia, parkinsonism and pyramidal signs associated with autonomic failure. Classically, cognitive impairment was not considered a clinical feature of MSA and dementia was pointed out as an exclusion diagnostic criteria. Based on comprehensive neuropsychological assessment, cognitive impairment was found to be a frequent feature in MSA, and clinically-defined dementia is now reported in 14-16% of cases. This article reviews the current data on cognitive impairment in MSA along with its neuropsychological profile and pathophysiology.info:eu-repo/semantics/openAccessAcademia Brasileira de Neurologia, Departamento de Neurologia Cognitiva e EnvelhecimentoDementia & Neuropsychologia v.5 n.4 20112011-12-01info:eu-repo/semantics/articletext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1980-57642011000400303en10.1590/S1980-57642011DN05040008
institution SCIELO
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country Brasil
countrycode BR
component Revista
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region America del Sur
libraryname SciELO
language English
format Digital
author Abrahão,Agessandro
Dutra,Livia Almeida
Braga Neto,Pedro
Pedroso,José Luiz
Oliveira,Ricardo Araújo de
Barsottini,Orlando Graziani Povoas
spellingShingle Abrahão,Agessandro
Dutra,Livia Almeida
Braga Neto,Pedro
Pedroso,José Luiz
Oliveira,Ricardo Araújo de
Barsottini,Orlando Graziani Povoas
Cognitive impairment in multiple system atrophy: Changing concepts
author_facet Abrahão,Agessandro
Dutra,Livia Almeida
Braga Neto,Pedro
Pedroso,José Luiz
Oliveira,Ricardo Araújo de
Barsottini,Orlando Graziani Povoas
author_sort Abrahão,Agessandro
title Cognitive impairment in multiple system atrophy: Changing concepts
title_short Cognitive impairment in multiple system atrophy: Changing concepts
title_full Cognitive impairment in multiple system atrophy: Changing concepts
title_fullStr Cognitive impairment in multiple system atrophy: Changing concepts
title_full_unstemmed Cognitive impairment in multiple system atrophy: Changing concepts
title_sort cognitive impairment in multiple system atrophy: changing concepts
description Abstract Multiple system atrophy (MSA) is characterized by a variable combination of cerebellar ataxia, parkinsonism and pyramidal signs associated with autonomic failure. Classically, cognitive impairment was not considered a clinical feature of MSA and dementia was pointed out as an exclusion diagnostic criteria. Based on comprehensive neuropsychological assessment, cognitive impairment was found to be a frequent feature in MSA, and clinically-defined dementia is now reported in 14-16% of cases. This article reviews the current data on cognitive impairment in MSA along with its neuropsychological profile and pathophysiology.
publisher Academia Brasileira de Neurologia, Departamento de Neurologia Cognitiva e Envelhecimento
publishDate 2011
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1980-57642011000400303
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AT barsottiniorlandograzianipovoas cognitiveimpairmentinmultiplesystematrophychangingconcepts
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