Significance of Extra-Esophageal Symptoms in Pediatric Gastroesophageal Reflux Disease
Abstract Introduction Current practice guidelines in gastroesophageal reflux disease (GERD) often require invasive diagnostic testing. Objective The aim of the present study was to evaluate the significance of extra-esophageal symptoms and reliability of a screening risk score that is simple to use. Methods A longitudinal retrospective single-institution cohort study. Setting: A university clinical hospital tertiary referral center. The present study enrolled pediatric patients with symptoms suggestive of GERD: epigastric pain, occasional nausea, regurgitation, tasting acid in the oral cavity, chronic cough, hoarseness of voice, frequent throat clearing. The patients underwent 24-hour esophageal pH monitoring and fiber-optic laryngoscopy. The correlations between the local findings, anamnestic and objective measurement data were analyzed. Results The present study evaluated 89 pediatric patients. Patients with asthma presented significantly more often with adjoining gastrointestinal symptoms (p = 0.0472). Patients that were obese were linked to a higher rate of reports of gastrointestinal symptoms (p = 0.0495). After the patients had been assigned to newly developed risk groups, obesity showed to be significantly more frequent in patients placed in higher risk groups (p < 0.0001) for a positive GERD diagnosis. Conclusion Patients with leading symptoms of asthma presented significantly more often with adjoining gastrointestinal symptoms. Obesity showed to be significantly more frequent in patients placed in higher risk groups for a positive GERD diagnosis.
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2020
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oai:scielo:S1809-486420200004004722020-11-13Significance of Extra-Esophageal Symptoms in Pediatric Gastroesophageal Reflux DiseaseKošec,AndroŽaja,OrjenaMatovinović,FilipJelavić,BorisBaudoin,Tomislav diagnostics obesity pediatric gastroesophageal reflux disease screening Abstract Introduction Current practice guidelines in gastroesophageal reflux disease (GERD) often require invasive diagnostic testing. Objective The aim of the present study was to evaluate the significance of extra-esophageal symptoms and reliability of a screening risk score that is simple to use. Methods A longitudinal retrospective single-institution cohort study. Setting: A university clinical hospital tertiary referral center. The present study enrolled pediatric patients with symptoms suggestive of GERD: epigastric pain, occasional nausea, regurgitation, tasting acid in the oral cavity, chronic cough, hoarseness of voice, frequent throat clearing. The patients underwent 24-hour esophageal pH monitoring and fiber-optic laryngoscopy. The correlations between the local findings, anamnestic and objective measurement data were analyzed. Results The present study evaluated 89 pediatric patients. Patients with asthma presented significantly more often with adjoining gastrointestinal symptoms (p = 0.0472). Patients that were obese were linked to a higher rate of reports of gastrointestinal symptoms (p = 0.0495). After the patients had been assigned to newly developed risk groups, obesity showed to be significantly more frequent in patients placed in higher risk groups (p < 0.0001) for a positive GERD diagnosis. Conclusion Patients with leading symptoms of asthma presented significantly more often with adjoining gastrointestinal symptoms. Obesity showed to be significantly more frequent in patients placed in higher risk groups for a positive GERD diagnosis.info:eu-repo/semantics/openAccessFundação OtorrinolaringologiaInternational Archives of Otorhinolaryngology v.24 n.4 20202020-12-01info:eu-repo/semantics/articletext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1809-48642020000400472en10.1055/s-0039-3402437 |
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Košec,Andro Žaja,Orjena Matovinović,Filip Jelavić,Boris Baudoin,Tomislav |
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Košec,Andro Žaja,Orjena Matovinović,Filip Jelavić,Boris Baudoin,Tomislav Significance of Extra-Esophageal Symptoms in Pediatric Gastroesophageal Reflux Disease |
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Košec,Andro Žaja,Orjena Matovinović,Filip Jelavić,Boris Baudoin,Tomislav |
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Košec,Andro |
title |
Significance of Extra-Esophageal Symptoms in Pediatric Gastroesophageal Reflux Disease |
title_short |
Significance of Extra-Esophageal Symptoms in Pediatric Gastroesophageal Reflux Disease |
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Significance of Extra-Esophageal Symptoms in Pediatric Gastroesophageal Reflux Disease |
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Significance of Extra-Esophageal Symptoms in Pediatric Gastroesophageal Reflux Disease |
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Significance of Extra-Esophageal Symptoms in Pediatric Gastroesophageal Reflux Disease |
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significance of extra-esophageal symptoms in pediatric gastroesophageal reflux disease |
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Abstract Introduction Current practice guidelines in gastroesophageal reflux disease (GERD) often require invasive diagnostic testing. Objective The aim of the present study was to evaluate the significance of extra-esophageal symptoms and reliability of a screening risk score that is simple to use. Methods A longitudinal retrospective single-institution cohort study. Setting: A university clinical hospital tertiary referral center. The present study enrolled pediatric patients with symptoms suggestive of GERD: epigastric pain, occasional nausea, regurgitation, tasting acid in the oral cavity, chronic cough, hoarseness of voice, frequent throat clearing. The patients underwent 24-hour esophageal pH monitoring and fiber-optic laryngoscopy. The correlations between the local findings, anamnestic and objective measurement data were analyzed. Results The present study evaluated 89 pediatric patients. Patients with asthma presented significantly more often with adjoining gastrointestinal symptoms (p = 0.0472). Patients that were obese were linked to a higher rate of reports of gastrointestinal symptoms (p = 0.0495). After the patients had been assigned to newly developed risk groups, obesity showed to be significantly more frequent in patients placed in higher risk groups (p < 0.0001) for a positive GERD diagnosis. Conclusion Patients with leading symptoms of asthma presented significantly more often with adjoining gastrointestinal symptoms. Obesity showed to be significantly more frequent in patients placed in higher risk groups for a positive GERD diagnosis. |
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2020 |
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