Salvage Retzius sparing robotic assisted radical prostatectomy: the first brazilian experience

ABSTRACT Introduction: Salvage Radical Prostatectomy after radiation therapy is challenging and associated with high rates of serious complications (1, 2). The novel Retzius-Sparing RARP (RS-RARP) approach has shown excellent continence outcomes (3, 4). Purpose: To describe step-by-step our Salvage Retzius-Sparing RARP (sRS-RARP) operative technique and report feasibility, safety and the preliminary oncological and continence outcomes in the post-radiation scenario. Materials and Methods: Twelve males presenting local prostate cancer recurrence after radiotherapy that underwent sRS-RARP were included. All patients performed preoperative multiparametric MRI and PSMA-PET. Surgical technique: 7cm peritoneum opening at Douglas pouch, Recto-prostatic space development, Seminal vesicles and vas deferens isolation and section, Extra-fascial dissection through peri-prostatic fat, Neurovascular bundle control, Bladder neck total preservation and opening, Anterior dissection at Santorini plexus plane, Apex dissection with urethra preservation and section, Prostate release, Vesicouretral modified Van Velthoveen anastomosis, Rocco Stitch, Oncological and continence outcomes reported with minimum 1-year follow-up. Results: Ten patients had previously received external beam radiation (EBR) whereas two received previous brachytherapy plus EBR. At 1, 3 and 12 months after surgery, 25%, 75% and 91.6% of the men used one safety pad or less, respectively. No major complications or blood transfusions were reported. Final pathology reported pT2b 41.6%, pT2c 33.3% and pT3a 25%, positive surgical margins 25%, positive lymph nodes were not found, biochemical recurrence 16.6%. Conclusion: Salvage Retzius-Sparing Robotic Assisted Radical Prostatectomy approach appears to be technically feasible and oncologically safe with potential to provide better continence outcomes.

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Main Authors: Nunes-Silva,Igor, Hidaka,Alexandre Kyoshi, Monti,Carlos Roberto, Tobias-Machado,Marcos, Zampolli,Hamilton de Campos
Format: Digital revista
Language:English
Published: Sociedade Brasileira de Urologia 2021
Online Access:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1677-55382021000601279
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spelling oai:scielo:S1677-553820210006012792021-09-29Salvage Retzius sparing robotic assisted radical prostatectomy: the first brazilian experienceNunes-Silva,IgorHidaka,Alexandre KyoshiMonti,Carlos RobertoTobias-Machado,MarcosZampolli,Hamilton de CamposABSTRACT Introduction: Salvage Radical Prostatectomy after radiation therapy is challenging and associated with high rates of serious complications (1, 2). The novel Retzius-Sparing RARP (RS-RARP) approach has shown excellent continence outcomes (3, 4). Purpose: To describe step-by-step our Salvage Retzius-Sparing RARP (sRS-RARP) operative technique and report feasibility, safety and the preliminary oncological and continence outcomes in the post-radiation scenario. Materials and Methods: Twelve males presenting local prostate cancer recurrence after radiotherapy that underwent sRS-RARP were included. All patients performed preoperative multiparametric MRI and PSMA-PET. Surgical technique: 7cm peritoneum opening at Douglas pouch, Recto-prostatic space development, Seminal vesicles and vas deferens isolation and section, Extra-fascial dissection through peri-prostatic fat, Neurovascular bundle control, Bladder neck total preservation and opening, Anterior dissection at Santorini plexus plane, Apex dissection with urethra preservation and section, Prostate release, Vesicouretral modified Van Velthoveen anastomosis, Rocco Stitch, Oncological and continence outcomes reported with minimum 1-year follow-up. Results: Ten patients had previously received external beam radiation (EBR) whereas two received previous brachytherapy plus EBR. At 1, 3 and 12 months after surgery, 25%, 75% and 91.6% of the men used one safety pad or less, respectively. No major complications or blood transfusions were reported. Final pathology reported pT2b 41.6%, pT2c 33.3% and pT3a 25%, positive surgical margins 25%, positive lymph nodes were not found, biochemical recurrence 16.6%. Conclusion: Salvage Retzius-Sparing Robotic Assisted Radical Prostatectomy approach appears to be technically feasible and oncologically safe with potential to provide better continence outcomes.info:eu-repo/semantics/openAccessSociedade Brasileira de UrologiaInternational braz j urol v.47 n.6 20212021-12-01info:eu-repo/semantics/othertext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1677-55382021000601279en10.1590/s1677-5538.ibju.2021.0260
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country Brasil
countrycode BR
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libraryname SciELO
language English
format Digital
author Nunes-Silva,Igor
Hidaka,Alexandre Kyoshi
Monti,Carlos Roberto
Tobias-Machado,Marcos
Zampolli,Hamilton de Campos
spellingShingle Nunes-Silva,Igor
Hidaka,Alexandre Kyoshi
Monti,Carlos Roberto
Tobias-Machado,Marcos
Zampolli,Hamilton de Campos
Salvage Retzius sparing robotic assisted radical prostatectomy: the first brazilian experience
author_facet Nunes-Silva,Igor
Hidaka,Alexandre Kyoshi
Monti,Carlos Roberto
Tobias-Machado,Marcos
Zampolli,Hamilton de Campos
author_sort Nunes-Silva,Igor
title Salvage Retzius sparing robotic assisted radical prostatectomy: the first brazilian experience
title_short Salvage Retzius sparing robotic assisted radical prostatectomy: the first brazilian experience
title_full Salvage Retzius sparing robotic assisted radical prostatectomy: the first brazilian experience
title_fullStr Salvage Retzius sparing robotic assisted radical prostatectomy: the first brazilian experience
title_full_unstemmed Salvage Retzius sparing robotic assisted radical prostatectomy: the first brazilian experience
title_sort salvage retzius sparing robotic assisted radical prostatectomy: the first brazilian experience
description ABSTRACT Introduction: Salvage Radical Prostatectomy after radiation therapy is challenging and associated with high rates of serious complications (1, 2). The novel Retzius-Sparing RARP (RS-RARP) approach has shown excellent continence outcomes (3, 4). Purpose: To describe step-by-step our Salvage Retzius-Sparing RARP (sRS-RARP) operative technique and report feasibility, safety and the preliminary oncological and continence outcomes in the post-radiation scenario. Materials and Methods: Twelve males presenting local prostate cancer recurrence after radiotherapy that underwent sRS-RARP were included. All patients performed preoperative multiparametric MRI and PSMA-PET. Surgical technique: 7cm peritoneum opening at Douglas pouch, Recto-prostatic space development, Seminal vesicles and vas deferens isolation and section, Extra-fascial dissection through peri-prostatic fat, Neurovascular bundle control, Bladder neck total preservation and opening, Anterior dissection at Santorini plexus plane, Apex dissection with urethra preservation and section, Prostate release, Vesicouretral modified Van Velthoveen anastomosis, Rocco Stitch, Oncological and continence outcomes reported with minimum 1-year follow-up. Results: Ten patients had previously received external beam radiation (EBR) whereas two received previous brachytherapy plus EBR. At 1, 3 and 12 months after surgery, 25%, 75% and 91.6% of the men used one safety pad or less, respectively. No major complications or blood transfusions were reported. Final pathology reported pT2b 41.6%, pT2c 33.3% and pT3a 25%, positive surgical margins 25%, positive lymph nodes were not found, biochemical recurrence 16.6%. Conclusion: Salvage Retzius-Sparing Robotic Assisted Radical Prostatectomy approach appears to be technically feasible and oncologically safe with potential to provide better continence outcomes.
publisher Sociedade Brasileira de Urologia
publishDate 2021
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1677-55382021000601279
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