Influence of expiration date on analytical performance of rapid tests for HIV diagnosis

Influence of expiration date on analytical performance of rapid tests for HIV diagnosis

ABSTRACT Introduction: Rapid tests (RTs) are ideal to provide laboratorial results within 30 minutes in a variety of situations and locations, even in underserved communities. Like any other laboratory input, they can only be used within the expiration date. Objective: The aim of this study was to compare the analytical performance of the RT Interkit HIV 1 and 2® (Interteck Katal - Belo Horizonte, Brazil) at two different times, two years before and one week before the expiration date. Material and methods: Two hundred serum samples were used, from individuals over 18 months of age, of both sexes, previously tested by electrochemiluminescence and Western Blot for HIV infection, distributed in two groups: reactive (n = 100) and non-reactive (n = 100). Results: The RT showed similar and satisfactory diagnostic accuracy in the two analyzed moments, with no statistical difference. Conclusion: The RT Interkit HIV 1 and 2® showed stable analytical performance both at the beginning and the end of its validity term.

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Main Authors: Marinho,Feliciana L. O., Santos,Nelson Luiz L., Neves,Suzane P. F., Vasconcellos,Leonardo S.
Format: Digital revista
Language:English
Published: Sociedade Brasileira de Patologia Clínica 2020
Online Access:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1676-24442020000100426
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spelling oai:scielo:S1676-244420200001004262020-11-10Influence of expiration date on analytical performance of rapid tests for HIV diagnosisMarinho,Feliciana L. O.Santos,Nelson Luiz L.Neves,Suzane P. F.Vasconcellos,Leonardo S. HIV diagnosis date of validity of products sensitivity specificity ABSTRACT Introduction: Rapid tests (RTs) are ideal to provide laboratorial results within 30 minutes in a variety of situations and locations, even in underserved communities. Like any other laboratory input, they can only be used within the expiration date. Objective: The aim of this study was to compare the analytical performance of the RT Interkit HIV 1 and 2® (Interteck Katal - Belo Horizonte, Brazil) at two different times, two years before and one week before the expiration date. Material and methods: Two hundred serum samples were used, from individuals over 18 months of age, of both sexes, previously tested by electrochemiluminescence and Western Blot for HIV infection, distributed in two groups: reactive (n = 100) and non-reactive (n = 100). Results: The RT showed similar and satisfactory diagnostic accuracy in the two analyzed moments, with no statistical difference. Conclusion: The RT Interkit HIV 1 and 2® showed stable analytical performance both at the beginning and the end of its validity term.info:eu-repo/semantics/openAccessSociedade Brasileira de Patologia Clínica Jornal Brasileiro de Patologia e Medicina Laboratorial v.56 20202020-01-01info:eu-repo/semantics/articletext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1676-24442020000100426en10.5935/1676-2444.20200055
institution SCIELO
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country Brasil
countrycode BR
component Revista
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databasecode rev-scielo-br
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region America del Sur
libraryname SciELO
language English
format Digital
author Marinho,Feliciana L. O.
Santos,Nelson Luiz L.
Neves,Suzane P. F.
Vasconcellos,Leonardo S.
spellingShingle Marinho,Feliciana L. O.
Santos,Nelson Luiz L.
Neves,Suzane P. F.
Vasconcellos,Leonardo S.
Influence of expiration date on analytical performance of rapid tests for HIV diagnosis
author_facet Marinho,Feliciana L. O.
Santos,Nelson Luiz L.
Neves,Suzane P. F.
Vasconcellos,Leonardo S.
author_sort Marinho,Feliciana L. O.
title Influence of expiration date on analytical performance of rapid tests for HIV diagnosis
title_short Influence of expiration date on analytical performance of rapid tests for HIV diagnosis
title_full Influence of expiration date on analytical performance of rapid tests for HIV diagnosis
title_fullStr Influence of expiration date on analytical performance of rapid tests for HIV diagnosis
title_full_unstemmed Influence of expiration date on analytical performance of rapid tests for HIV diagnosis
title_sort influence of expiration date on analytical performance of rapid tests for hiv diagnosis
description ABSTRACT Introduction: Rapid tests (RTs) are ideal to provide laboratorial results within 30 minutes in a variety of situations and locations, even in underserved communities. Like any other laboratory input, they can only be used within the expiration date. Objective: The aim of this study was to compare the analytical performance of the RT Interkit HIV 1 and 2® (Interteck Katal - Belo Horizonte, Brazil) at two different times, two years before and one week before the expiration date. Material and methods: Two hundred serum samples were used, from individuals over 18 months of age, of both sexes, previously tested by electrochemiluminescence and Western Blot for HIV infection, distributed in two groups: reactive (n = 100) and non-reactive (n = 100). Results: The RT showed similar and satisfactory diagnostic accuracy in the two analyzed moments, with no statistical difference. Conclusion: The RT Interkit HIV 1 and 2® showed stable analytical performance both at the beginning and the end of its validity term.
publisher Sociedade Brasileira de Patologia Clínica
publishDate 2020
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1676-24442020000100426
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AT vasconcellosleonardos influenceofexpirationdateonanalyticalperformanceofrapidtestsforhivdiagnosis
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