Production of chemically modified chitosan microspheres by a spraying and coagulation method
Chitosan microspheres can be used in several applications, as biomaterials, in biotechnology processes and as adsorbents. The control of particle size in microsphere production is important to make these applications viable. This study focuses on the production and morphological characterization of chitosan microspheres. Microspheres were prepared by a spraying and coagulation process. Particles underwent chemical modifications with glutaraldehyde, epichlorohydrin or acetic anhydride treatments. The microspheres presented a fairly good sphericity (0.74) but an irregular micro-surface morphology. The mean particle size (MPS) ranged from 140 to 281 mum and the mean standard deviation (MSD) from 119 to 238 mm. The conditions were modelled to provide desired MPS and MSD by using the response surface methodology (RSM).
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ABM, ABC, ABPol
2007
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oai:scielo:S1516-143920070004000052008-02-07Production of chemically modified chitosan microspheres by a spraying and coagulation methodTorres,Marco AntonioVieira,Rodrigo SilveiraBeppu,Marisa MasumiArruda,Eduardo JoséSantana,Cesar Costapinto chitosan microspheres Chitosan microspheres can be used in several applications, as biomaterials, in biotechnology processes and as adsorbents. The control of particle size in microsphere production is important to make these applications viable. This study focuses on the production and morphological characterization of chitosan microspheres. Microspheres were prepared by a spraying and coagulation process. Particles underwent chemical modifications with glutaraldehyde, epichlorohydrin or acetic anhydride treatments. The microspheres presented a fairly good sphericity (0.74) but an irregular micro-surface morphology. The mean particle size (MPS) ranged from 140 to 281 mum and the mean standard deviation (MSD) from 119 to 238 mm. The conditions were modelled to provide desired MPS and MSD by using the response surface methodology (RSM).info:eu-repo/semantics/openAccessABM, ABC, ABPolMaterials Research v.10 n.4 20072007-12-01info:eu-repo/semantics/articletext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-14392007000400005en10.1590/S1516-14392007000400005 |
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Torres,Marco Antonio Vieira,Rodrigo Silveira Beppu,Marisa Masumi Arruda,Eduardo José Santana,Cesar Costapinto |
| spellingShingle |
Torres,Marco Antonio Vieira,Rodrigo Silveira Beppu,Marisa Masumi Arruda,Eduardo José Santana,Cesar Costapinto Production of chemically modified chitosan microspheres by a spraying and coagulation method |
| author_facet |
Torres,Marco Antonio Vieira,Rodrigo Silveira Beppu,Marisa Masumi Arruda,Eduardo José Santana,Cesar Costapinto |
| author_sort |
Torres,Marco Antonio |
| title |
Production of chemically modified chitosan microspheres by a spraying and coagulation method |
| title_short |
Production of chemically modified chitosan microspheres by a spraying and coagulation method |
| title_full |
Production of chemically modified chitosan microspheres by a spraying and coagulation method |
| title_fullStr |
Production of chemically modified chitosan microspheres by a spraying and coagulation method |
| title_full_unstemmed |
Production of chemically modified chitosan microspheres by a spraying and coagulation method |
| title_sort |
production of chemically modified chitosan microspheres by a spraying and coagulation method |
| description |
Chitosan microspheres can be used in several applications, as biomaterials, in biotechnology processes and as adsorbents. The control of particle size in microsphere production is important to make these applications viable. This study focuses on the production and morphological characterization of chitosan microspheres. Microspheres were prepared by a spraying and coagulation process. Particles underwent chemical modifications with glutaraldehyde, epichlorohydrin or acetic anhydride treatments. The microspheres presented a fairly good sphericity (0.74) but an irregular micro-surface morphology. The mean particle size (MPS) ranged from 140 to 281 mum and the mean standard deviation (MSD) from 119 to 238 mm. The conditions were modelled to provide desired MPS and MSD by using the response surface methodology (RSM). |
| publisher |
ABM, ABC, ABPol |
| publishDate |
2007 |
| url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-14392007000400005 |
| work_keys_str_mv |
AT torresmarcoantonio productionofchemicallymodifiedchitosanmicrospheresbyasprayingandcoagulationmethod AT vieirarodrigosilveira productionofchemicallymodifiedchitosanmicrospheresbyasprayingandcoagulationmethod AT beppumarisamasumi productionofchemicallymodifiedchitosanmicrospheresbyasprayingandcoagulationmethod AT arrudaeduardojose productionofchemicallymodifiedchitosanmicrospheresbyasprayingandcoagulationmethod AT santanacesarcostapinto productionofchemicallymodifiedchitosanmicrospheresbyasprayingandcoagulationmethod |
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1756420335070085120 |