Brazil in the face of new SARS-CoV-2 variants: emergencies and challenges in public health

ABSTRACT: This article discusses the epidemic situation of Covid-19 in Brazil, in the face of the emergence of a new strain called P.1, which is more transmissible and may be associated with reinfection. Given the collapse of hospital care in Manaus in January 2021 and the results of three recent preprints, each that reports increased transmissibility of the P.1 variant, we propose some urgent measures. Genomic surveillance based on multi-step diagnostics, starting with RT-PCR type tests and up to sequencing, should be established. Efforts to identify reinfections associated with this variant and the update of its definition in protocols should be prioritized, and studies on the efficacy of currently available vaccines in Brazil concerning the new variant should be conducted. We also propose improving the Brazilian health surveillance system such that genomic surveillance is coordinated and thereby better able to respond to future emergencies in a more timely fashion. We call on the public agents involved in health surveillance to share data and information regarding the epidemic in a clear, fast and transparent way. Finally, we propose a greater engagement in inter-institutional cooperation of all those involved in the response and production of knowledge about the pandemic in our country.

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Main Authors: Marquitti,Flavia Maria Darcie, Coutinho,Renato Mendes, Ferreira,Leonardo Souto, Borges,Marcelo Eduardo, Portella,Tatiana Pineda, Silva,Rafael Lopes Paixão da, Canton,Otavio, Poloni,Silas, Franco,Caroline, Coelho,Verônica, Barberia,Lorena, Bolle,Monica de, Boing,Alexandra Crispim, Donalisio,Maria Rita, Boing,Antonio Fernando, Silva,Antônio Augusto Moura da, Prado,Paulo Inácio, Veras,Maria Amélia de Sousa Mascena, Kraenkel,Roberto André
Format: Digital revista
Language:English
Published: Associação Brasileira de Saúde Coletiva 2021
Online Access:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1415-790X2021000100204
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spelling oai:scielo:S1415-790X20210001002042021-06-02Brazil in the face of new SARS-CoV-2 variants: emergencies and challenges in public healthMarquitti,Flavia Maria DarcieCoutinho,Renato MendesFerreira,Leonardo SoutoBorges,Marcelo EduardoPortella,Tatiana PinedaSilva,Rafael Lopes Paixão daCanton,OtavioPoloni,SilasFranco,CarolineCoelho,VerônicaBarberia,LorenaBolle,Monica deBoing,Alexandra CrispimDonalisio,Maria RitaBoing,Antonio FernandoSilva,Antônio Augusto Moura daPrado,Paulo InácioVeras,Maria Amélia de Sousa MascenaKraenkel,Roberto André Coronavirus infections Surveillance Epidemics ABSTRACT: This article discusses the epidemic situation of Covid-19 in Brazil, in the face of the emergence of a new strain called P.1, which is more transmissible and may be associated with reinfection. Given the collapse of hospital care in Manaus in January 2021 and the results of three recent preprints, each that reports increased transmissibility of the P.1 variant, we propose some urgent measures. Genomic surveillance based on multi-step diagnostics, starting with RT-PCR type tests and up to sequencing, should be established. Efforts to identify reinfections associated with this variant and the update of its definition in protocols should be prioritized, and studies on the efficacy of currently available vaccines in Brazil concerning the new variant should be conducted. We also propose improving the Brazilian health surveillance system such that genomic surveillance is coordinated and thereby better able to respond to future emergencies in a more timely fashion. We call on the public agents involved in health surveillance to share data and information regarding the epidemic in a clear, fast and transparent way. Finally, we propose a greater engagement in inter-institutional cooperation of all those involved in the response and production of knowledge about the pandemic in our country.info:eu-repo/semantics/openAccessAssociação Brasileira de Saúde ColetivaRevista Brasileira de Epidemiologia v.24 20212021-01-01info:eu-repo/semantics/articletext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1415-790X2021000100204en10.1590/1980-549720210022
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language English
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author Marquitti,Flavia Maria Darcie
Coutinho,Renato Mendes
Ferreira,Leonardo Souto
Borges,Marcelo Eduardo
Portella,Tatiana Pineda
Silva,Rafael Lopes Paixão da
Canton,Otavio
Poloni,Silas
Franco,Caroline
Coelho,Verônica
Barberia,Lorena
Bolle,Monica de
Boing,Alexandra Crispim
Donalisio,Maria Rita
Boing,Antonio Fernando
Silva,Antônio Augusto Moura da
Prado,Paulo Inácio
Veras,Maria Amélia de Sousa Mascena
Kraenkel,Roberto André
spellingShingle Marquitti,Flavia Maria Darcie
Coutinho,Renato Mendes
Ferreira,Leonardo Souto
Borges,Marcelo Eduardo
Portella,Tatiana Pineda
Silva,Rafael Lopes Paixão da
Canton,Otavio
Poloni,Silas
Franco,Caroline
Coelho,Verônica
Barberia,Lorena
Bolle,Monica de
Boing,Alexandra Crispim
Donalisio,Maria Rita
Boing,Antonio Fernando
Silva,Antônio Augusto Moura da
Prado,Paulo Inácio
Veras,Maria Amélia de Sousa Mascena
Kraenkel,Roberto André
Brazil in the face of new SARS-CoV-2 variants: emergencies and challenges in public health
author_facet Marquitti,Flavia Maria Darcie
Coutinho,Renato Mendes
Ferreira,Leonardo Souto
Borges,Marcelo Eduardo
Portella,Tatiana Pineda
Silva,Rafael Lopes Paixão da
Canton,Otavio
Poloni,Silas
Franco,Caroline
Coelho,Verônica
Barberia,Lorena
Bolle,Monica de
Boing,Alexandra Crispim
Donalisio,Maria Rita
Boing,Antonio Fernando
Silva,Antônio Augusto Moura da
Prado,Paulo Inácio
Veras,Maria Amélia de Sousa Mascena
Kraenkel,Roberto André
author_sort Marquitti,Flavia Maria Darcie
title Brazil in the face of new SARS-CoV-2 variants: emergencies and challenges in public health
title_short Brazil in the face of new SARS-CoV-2 variants: emergencies and challenges in public health
title_full Brazil in the face of new SARS-CoV-2 variants: emergencies and challenges in public health
title_fullStr Brazil in the face of new SARS-CoV-2 variants: emergencies and challenges in public health
title_full_unstemmed Brazil in the face of new SARS-CoV-2 variants: emergencies and challenges in public health
title_sort brazil in the face of new sars-cov-2 variants: emergencies and challenges in public health
description ABSTRACT: This article discusses the epidemic situation of Covid-19 in Brazil, in the face of the emergence of a new strain called P.1, which is more transmissible and may be associated with reinfection. Given the collapse of hospital care in Manaus in January 2021 and the results of three recent preprints, each that reports increased transmissibility of the P.1 variant, we propose some urgent measures. Genomic surveillance based on multi-step diagnostics, starting with RT-PCR type tests and up to sequencing, should be established. Efforts to identify reinfections associated with this variant and the update of its definition in protocols should be prioritized, and studies on the efficacy of currently available vaccines in Brazil concerning the new variant should be conducted. We also propose improving the Brazilian health surveillance system such that genomic surveillance is coordinated and thereby better able to respond to future emergencies in a more timely fashion. We call on the public agents involved in health surveillance to share data and information regarding the epidemic in a clear, fast and transparent way. Finally, we propose a greater engagement in inter-institutional cooperation of all those involved in the response and production of knowledge about the pandemic in our country.
publisher Associação Brasileira de Saúde Coletiva
publishDate 2021
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1415-790X2021000100204
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