Emergence of Klebsiella pneumoniae-producing KPC-2 carbapenemase in Paraíba, Northeastern Brazil

The emergence of KPC-2 producing K. pneumoniae in hospitalized patients at the intensive care unit (ICU) of a teaching hospital located in the city of João Pessoa, Paraíba, Brazil, is reported. Seven carbapenem-resistant K. pneumoniae recovered from different body sites of infection were analyzed. Most isolates showed a multidrug-resistance phenotype. Genotypic analysis demonstrated the presence of two genotypes, with the predominance of genotype A, which belongs to ST 437. These isolates also carry the encoding genes of five other betalactamases.

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Main Authors: Fehlberg,Lorena C.C., Carvalho,Albalucia M.C., Campana,Eloiza H., Gontijo-Filho,Paulo P., Gales,Ana C.
Format: Digital revista
Language:English
Published: Brazilian Society of Infectious Diseases 2012
Online Access:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702012000600013
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spelling oai:scielo:S1413-867020120006000132013-02-20Emergence of Klebsiella pneumoniae-producing KPC-2 carbapenemase in Paraíba, Northeastern BrazilFehlberg,Lorena C.C.Carvalho,Albalucia M.C.Campana,Eloiza H.Gontijo-Filho,Paulo P.Gales,Ana C. Beta-lactam resistance Modified Hodge test Carbapenem resistance Enterobacteriaceae The emergence of KPC-2 producing K. pneumoniae in hospitalized patients at the intensive care unit (ICU) of a teaching hospital located in the city of João Pessoa, Paraíba, Brazil, is reported. Seven carbapenem-resistant K. pneumoniae recovered from different body sites of infection were analyzed. Most isolates showed a multidrug-resistance phenotype. Genotypic analysis demonstrated the presence of two genotypes, with the predominance of genotype A, which belongs to ST 437. These isolates also carry the encoding genes of five other betalactamases.info:eu-repo/semantics/openAccessBrazilian Society of Infectious DiseasesBrazilian Journal of Infectious Diseases v.16 n.6 20122012-12-01info:eu-repo/semantics/othertext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702012000600013en10.1016/j.bjid.2012.07.001
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country Brasil
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language English
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author Fehlberg,Lorena C.C.
Carvalho,Albalucia M.C.
Campana,Eloiza H.
Gontijo-Filho,Paulo P.
Gales,Ana C.
spellingShingle Fehlberg,Lorena C.C.
Carvalho,Albalucia M.C.
Campana,Eloiza H.
Gontijo-Filho,Paulo P.
Gales,Ana C.
Emergence of Klebsiella pneumoniae-producing KPC-2 carbapenemase in Paraíba, Northeastern Brazil
author_facet Fehlberg,Lorena C.C.
Carvalho,Albalucia M.C.
Campana,Eloiza H.
Gontijo-Filho,Paulo P.
Gales,Ana C.
author_sort Fehlberg,Lorena C.C.
title Emergence of Klebsiella pneumoniae-producing KPC-2 carbapenemase in Paraíba, Northeastern Brazil
title_short Emergence of Klebsiella pneumoniae-producing KPC-2 carbapenemase in Paraíba, Northeastern Brazil
title_full Emergence of Klebsiella pneumoniae-producing KPC-2 carbapenemase in Paraíba, Northeastern Brazil
title_fullStr Emergence of Klebsiella pneumoniae-producing KPC-2 carbapenemase in Paraíba, Northeastern Brazil
title_full_unstemmed Emergence of Klebsiella pneumoniae-producing KPC-2 carbapenemase in Paraíba, Northeastern Brazil
title_sort emergence of klebsiella pneumoniae-producing kpc-2 carbapenemase in paraíba, northeastern brazil
description The emergence of KPC-2 producing K. pneumoniae in hospitalized patients at the intensive care unit (ICU) of a teaching hospital located in the city of João Pessoa, Paraíba, Brazil, is reported. Seven carbapenem-resistant K. pneumoniae recovered from different body sites of infection were analyzed. Most isolates showed a multidrug-resistance phenotype. Genotypic analysis demonstrated the presence of two genotypes, with the predominance of genotype A, which belongs to ST 437. These isolates also carry the encoding genes of five other betalactamases.
publisher Brazilian Society of Infectious Diseases
publishDate 2012
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702012000600013
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