Molecular characterization of van genes found in vancomycin-resistant Enterococcus spp. isolated from Hospital das Clínicas, FMUSP, São Paulo, Brazil

Molecular characterization of van genes found in vancomycin-resistant Enterococcus spp. isolated from Hospital das Clínicas, FMUSP, São Paulo, Brazil

Vancomycin-resistant enterococci strains (VRE) is an important pathogen related with hospital infections in many countries, presenting limited or no therapeutic options for treating serious infections. VRE has presented some different genotypes been VanA and VanB considered to be the most important in hospital environments. In the present study the authors investigated the prevalence of van genes (A, B an C) among clinical isolates of VRE in a five month period at a large tertiary hospital in Sao Paulo, Brazil. The results showed the presence of vanA, but not vanB or vanC in all 43 strains of E. faecalis and five E. faecium studied. The results bring an important issue, due to the possibility of resistance spread of vanA genes, to be monitored and solved by the hospital infection control team and the microbiology and molecular biology laboratories at tertiary Hospitals.

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Main Authors: Caiaffa Filho,H.H., Almeida,G.D., Oliveira,G.A., Sarahyba,L., Mamizuka,E.M., Burattini,M.N.
Format: Digital revista
Language:English
Published: Brazilian Society of Infectious Diseases 2003
Online Access:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702003000300001
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spelling oai:scielo:S1413-867020030003000012003-12-08Molecular characterization of van genes found in vancomycin-resistant Enterococcus spp. isolated from Hospital das Clínicas, FMUSP, São Paulo, BrazilCaiaffa Filho,H.H.Almeida,G.D.Oliveira,G.A.Sarahyba,L.Mamizuka,E.M.Burattini,M.N. Enterococci vancomycin resistance hospital infections Vancomycin-resistant enterococci strains (VRE) is an important pathogen related with hospital infections in many countries, presenting limited or no therapeutic options for treating serious infections. VRE has presented some different genotypes been VanA and VanB considered to be the most important in hospital environments. In the present study the authors investigated the prevalence of van genes (A, B an C) among clinical isolates of VRE in a five month period at a large tertiary hospital in Sao Paulo, Brazil. The results showed the presence of vanA, but not vanB or vanC in all 43 strains of E. faecalis and five E. faecium studied. The results bring an important issue, due to the possibility of resistance spread of vanA genes, to be monitored and solved by the hospital infection control team and the microbiology and molecular biology laboratories at tertiary Hospitals.info:eu-repo/semantics/openAccessBrazilian Society of Infectious DiseasesBrazilian Journal of Infectious Diseases v.7 n.3 20032003-06-01info:eu-repo/semantics/othertext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702003000300001en10.1590/S1413-86702003000300001
institution SCIELO
collection OJS
country Brasil
countrycode BR
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region America del Sur
libraryname SciELO
language English
format Digital
author Caiaffa Filho,H.H.
Almeida,G.D.
Oliveira,G.A.
Sarahyba,L.
Mamizuka,E.M.
Burattini,M.N.
spellingShingle Caiaffa Filho,H.H.
Almeida,G.D.
Oliveira,G.A.
Sarahyba,L.
Mamizuka,E.M.
Burattini,M.N.
Molecular characterization of van genes found in vancomycin-resistant Enterococcus spp. isolated from Hospital das Clínicas, FMUSP, São Paulo, Brazil
author_facet Caiaffa Filho,H.H.
Almeida,G.D.
Oliveira,G.A.
Sarahyba,L.
Mamizuka,E.M.
Burattini,M.N.
author_sort Caiaffa Filho,H.H.
title Molecular characterization of van genes found in vancomycin-resistant Enterococcus spp. isolated from Hospital das Clínicas, FMUSP, São Paulo, Brazil
title_short Molecular characterization of van genes found in vancomycin-resistant Enterococcus spp. isolated from Hospital das Clínicas, FMUSP, São Paulo, Brazil
title_full Molecular characterization of van genes found in vancomycin-resistant Enterococcus spp. isolated from Hospital das Clínicas, FMUSP, São Paulo, Brazil
title_fullStr Molecular characterization of van genes found in vancomycin-resistant Enterococcus spp. isolated from Hospital das Clínicas, FMUSP, São Paulo, Brazil
title_full_unstemmed Molecular characterization of van genes found in vancomycin-resistant Enterococcus spp. isolated from Hospital das Clínicas, FMUSP, São Paulo, Brazil
title_sort molecular characterization of van genes found in vancomycin-resistant enterococcus spp. isolated from hospital das clínicas, fmusp, são paulo, brazil
description Vancomycin-resistant enterococci strains (VRE) is an important pathogen related with hospital infections in many countries, presenting limited or no therapeutic options for treating serious infections. VRE has presented some different genotypes been VanA and VanB considered to be the most important in hospital environments. In the present study the authors investigated the prevalence of van genes (A, B an C) among clinical isolates of VRE in a five month period at a large tertiary hospital in Sao Paulo, Brazil. The results showed the presence of vanA, but not vanB or vanC in all 43 strains of E. faecalis and five E. faecium studied. The results bring an important issue, due to the possibility of resistance spread of vanA genes, to be monitored and solved by the hospital infection control team and the microbiology and molecular biology laboratories at tertiary Hospitals.
publisher Brazilian Society of Infectious Diseases
publishDate 2003
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702003000300001
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