Photosensitive rash induced by nivolumab

Abstract The therapeutic approach to metastatic melanoma has revolutionized the clinical course of this disease. Since 2011, different immunotherapeutic drugs have been approved. Nivolumab is a humanized immunoglobulin IgG4 monoclonal antibody that binds to the PD-1 receptor, blocking its interaction with his ligand PD-L1. The authors present a new case of photosensitivity induced by nivolumab. The photo exposed distribution of the eruption, the sun exposure prior to the beginning of the eruption, and the chronological relationship with the beginning of the treatment are data that have allowed us to confirm the suspected clinical diagnosis.

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Main Authors: Navarro-Triviño,Francisco J., Ruiz-Villaverde,Ricardo
Format: Digital revista
Language:English
Published: Sociedade Brasileira de Dermatologia 2022
Online Access:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962022000500648
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spelling oai:scielo:S0365-059620220005006482022-09-27Photosensitive rash induced by nivolumabNavarro-Triviño,Francisco J.Ruiz-Villaverde,Ricardo Melanoma Patch tests Photobiology Abstract The therapeutic approach to metastatic melanoma has revolutionized the clinical course of this disease. Since 2011, different immunotherapeutic drugs have been approved. Nivolumab is a humanized immunoglobulin IgG4 monoclonal antibody that binds to the PD-1 receptor, blocking its interaction with his ligand PD-L1. The authors present a new case of photosensitivity induced by nivolumab. The photo exposed distribution of the eruption, the sun exposure prior to the beginning of the eruption, and the chronological relationship with the beginning of the treatment are data that have allowed us to confirm the suspected clinical diagnosis.info:eu-repo/semantics/openAccessSociedade Brasileira de DermatologiaAnais Brasileiros de Dermatologia v.97 n.5 20222022-10-01info:eu-repo/semantics/articletext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962022000500648en10.1016/j.abd.2021.07.007
institution SCIELO
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country Brasil
countrycode BR
component Revista
access En linea
databasecode rev-scielo-br
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region America del Sur
libraryname SciELO
language English
format Digital
author Navarro-Triviño,Francisco J.
Ruiz-Villaverde,Ricardo
spellingShingle Navarro-Triviño,Francisco J.
Ruiz-Villaverde,Ricardo
Photosensitive rash induced by nivolumab
author_facet Navarro-Triviño,Francisco J.
Ruiz-Villaverde,Ricardo
author_sort Navarro-Triviño,Francisco J.
title Photosensitive rash induced by nivolumab
title_short Photosensitive rash induced by nivolumab
title_full Photosensitive rash induced by nivolumab
title_fullStr Photosensitive rash induced by nivolumab
title_full_unstemmed Photosensitive rash induced by nivolumab
title_sort photosensitive rash induced by nivolumab
description Abstract The therapeutic approach to metastatic melanoma has revolutionized the clinical course of this disease. Since 2011, different immunotherapeutic drugs have been approved. Nivolumab is a humanized immunoglobulin IgG4 monoclonal antibody that binds to the PD-1 receptor, blocking its interaction with his ligand PD-L1. The authors present a new case of photosensitivity induced by nivolumab. The photo exposed distribution of the eruption, the sun exposure prior to the beginning of the eruption, and the chronological relationship with the beginning of the treatment are data that have allowed us to confirm the suspected clinical diagnosis.
publisher Sociedade Brasileira de Dermatologia
publishDate 2022
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962022000500648
work_keys_str_mv AT navarrotrivinofranciscoj photosensitiverashinducedbynivolumab
AT ruizvillaverdericardo photosensitiverashinducedbynivolumab
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