Photodynamic action of the red laser on Propionibacterium acnes
Abstract: Background: Photodynamic therapy is a therapeutic modality that has consolidated its activity in the photooxidation of organic matter, which arises from the activity of reactive oxygen species. Objective: To evaluate the effect of red laser 660nm with the photosensitizer methylene blue on Propionibacterium acnes in vitro. Method: The experimental design was distributed into four groups (1 - control group without the application of light and without photosensitizer, 2 - application of light, 3 - methylene blue without light, and 4 - methylene blue with light). Tests were subjected to red laser irradiation 660nm by four cycles of 5 minutes at 3-minute intervals. Results: It was evidenced the prominence of the fourth cycle (20 minutes) groups 2, 3 and 4. Study limitations: Despite the favorable results, the laser irradiation time photosensitizer associated with methylene blue were not sufficient to to completely inhibit the proliferation of bacteria. Conclusion: Further studies in vitro are recommended to enable the clinical application of this photosensitizer in photodynamic therapy.
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Sociedade Brasileira de Dermatologia
2017
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oai:scielo:S0365-059620170005006222017-11-14Photodynamic action of the red laser on Propionibacterium acnesRamos,Rogério RodrigoPaiva,Jeferson Leandro deGomes,José Paulo Franco dos SantosBoer,Nagib PezatiGodoy,José Maria Pereira deBatigalia,Fernando Laser therapy Methylene blue Propionibacterium acnes Abstract: Background: Photodynamic therapy is a therapeutic modality that has consolidated its activity in the photooxidation of organic matter, which arises from the activity of reactive oxygen species. Objective: To evaluate the effect of red laser 660nm with the photosensitizer methylene blue on Propionibacterium acnes in vitro. Method: The experimental design was distributed into four groups (1 - control group without the application of light and without photosensitizer, 2 - application of light, 3 - methylene blue without light, and 4 - methylene blue with light). Tests were subjected to red laser irradiation 660nm by four cycles of 5 minutes at 3-minute intervals. Results: It was evidenced the prominence of the fourth cycle (20 minutes) groups 2, 3 and 4. Study limitations: Despite the favorable results, the laser irradiation time photosensitizer associated with methylene blue were not sufficient to to completely inhibit the proliferation of bacteria. Conclusion: Further studies in vitro are recommended to enable the clinical application of this photosensitizer in photodynamic therapy.info:eu-repo/semantics/openAccessSociedade Brasileira de DermatologiaAnais Brasileiros de Dermatologia v.92 n.5 20172017-10-01info:eu-repo/semantics/articletext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962017000500622en10.1590/abd1806-4841.20175651 |
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Ramos,Rogério Rodrigo Paiva,Jeferson Leandro de Gomes,José Paulo Franco dos Santos Boer,Nagib Pezati Godoy,José Maria Pereira de Batigalia,Fernando |
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Ramos,Rogério Rodrigo Paiva,Jeferson Leandro de Gomes,José Paulo Franco dos Santos Boer,Nagib Pezati Godoy,José Maria Pereira de Batigalia,Fernando Photodynamic action of the red laser on Propionibacterium acnes |
| author_facet |
Ramos,Rogério Rodrigo Paiva,Jeferson Leandro de Gomes,José Paulo Franco dos Santos Boer,Nagib Pezati Godoy,José Maria Pereira de Batigalia,Fernando |
| author_sort |
Ramos,Rogério Rodrigo |
| title |
Photodynamic action of the red laser on Propionibacterium acnes |
| title_short |
Photodynamic action of the red laser on Propionibacterium acnes |
| title_full |
Photodynamic action of the red laser on Propionibacterium acnes |
| title_fullStr |
Photodynamic action of the red laser on Propionibacterium acnes |
| title_full_unstemmed |
Photodynamic action of the red laser on Propionibacterium acnes |
| title_sort |
photodynamic action of the red laser on propionibacterium acnes |
| description |
Abstract: Background: Photodynamic therapy is a therapeutic modality that has consolidated its activity in the photooxidation of organic matter, which arises from the activity of reactive oxygen species. Objective: To evaluate the effect of red laser 660nm with the photosensitizer methylene blue on Propionibacterium acnes in vitro. Method: The experimental design was distributed into four groups (1 - control group without the application of light and without photosensitizer, 2 - application of light, 3 - methylene blue without light, and 4 - methylene blue with light). Tests were subjected to red laser irradiation 660nm by four cycles of 5 minutes at 3-minute intervals. Results: It was evidenced the prominence of the fourth cycle (20 minutes) groups 2, 3 and 4. Study limitations: Despite the favorable results, the laser irradiation time photosensitizer associated with methylene blue were not sufficient to to completely inhibit the proliferation of bacteria. Conclusion: Further studies in vitro are recommended to enable the clinical application of this photosensitizer in photodynamic therapy. |
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Sociedade Brasileira de Dermatologia |
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2017 |
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http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962017000500622 |
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