Cutaneous metastasis as the first manifestation of occult malignant breast neoplasia
Abstract Cutaneous metastases from primary internal malignancies represent 0.7-9% of patients with cancer. We report a 65-year-old female patient referred for evaluation of normochromic papules on the trunk and upper limbs that had been present for three months. A skin biopsy revealed diffuse cutaneous infiltration by small round cell tumors. Immunohistochemistry was positive for AE1/AE3, CK7, estrogen receptor and mammaglobin. The final diagnosis was cutaneous metastasis of occult breast cancer, since the solid primary tumor was not identified. The location of the primary tumor can not be determined in 5-10% of cases. In these cases, 27% are identified before the patient’s death, 57% at autopsy, and the remaining 16% can not be located.
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Sociedade Brasileira de Dermatologia
2016
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oai:scielo:S0365-059620160011001052017-03-03Cutaneous metastasis as the first manifestation of occult malignant breast neoplasiaWeimann,Ellem Tatiani de SouzaBotero,Erica BruderMendes,CinthiaSantos,Marcel Alex Soares dosStelini,Rafael FantelliZelenika,Caroline Romanelli T. Breast neoplasms Neoplasm metastasis Skin Abstract Cutaneous metastases from primary internal malignancies represent 0.7-9% of patients with cancer. We report a 65-year-old female patient referred for evaluation of normochromic papules on the trunk and upper limbs that had been present for three months. A skin biopsy revealed diffuse cutaneous infiltration by small round cell tumors. Immunohistochemistry was positive for AE1/AE3, CK7, estrogen receptor and mammaglobin. The final diagnosis was cutaneous metastasis of occult breast cancer, since the solid primary tumor was not identified. The location of the primary tumor can not be determined in 5-10% of cases. In these cases, 27% are identified before the patient’s death, 57% at autopsy, and the remaining 16% can not be located.info:eu-repo/semantics/openAccessSociedade Brasileira de DermatologiaAnais Brasileiros de Dermatologia v.91 n.5 suppl.1 20162016-10-01info:eu-repo/semantics/reporttext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962016001100105en10.1590/abd1806-4841.20164572 |
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Weimann,Ellem Tatiani de Souza Botero,Erica Bruder Mendes,Cinthia Santos,Marcel Alex Soares dos Stelini,Rafael Fantelli Zelenika,Caroline Romanelli T. |
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Weimann,Ellem Tatiani de Souza Botero,Erica Bruder Mendes,Cinthia Santos,Marcel Alex Soares dos Stelini,Rafael Fantelli Zelenika,Caroline Romanelli T. Cutaneous metastasis as the first manifestation of occult malignant breast neoplasia |
| author_facet |
Weimann,Ellem Tatiani de Souza Botero,Erica Bruder Mendes,Cinthia Santos,Marcel Alex Soares dos Stelini,Rafael Fantelli Zelenika,Caroline Romanelli T. |
| author_sort |
Weimann,Ellem Tatiani de Souza |
| title |
Cutaneous metastasis as the first manifestation of occult malignant breast neoplasia |
| title_short |
Cutaneous metastasis as the first manifestation of occult malignant breast neoplasia |
| title_full |
Cutaneous metastasis as the first manifestation of occult malignant breast neoplasia |
| title_fullStr |
Cutaneous metastasis as the first manifestation of occult malignant breast neoplasia |
| title_full_unstemmed |
Cutaneous metastasis as the first manifestation of occult malignant breast neoplasia |
| title_sort |
cutaneous metastasis as the first manifestation of occult malignant breast neoplasia |
| description |
Abstract Cutaneous metastases from primary internal malignancies represent 0.7-9% of patients with cancer. We report a 65-year-old female patient referred for evaluation of normochromic papules on the trunk and upper limbs that had been present for three months. A skin biopsy revealed diffuse cutaneous infiltration by small round cell tumors. Immunohistochemistry was positive for AE1/AE3, CK7, estrogen receptor and mammaglobin. The final diagnosis was cutaneous metastasis of occult breast cancer, since the solid primary tumor was not identified. The location of the primary tumor can not be determined in 5-10% of cases. In these cases, 27% are identified before the patient’s death, 57% at autopsy, and the remaining 16% can not be located. |
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Sociedade Brasileira de Dermatologia |
| publishDate |
2016 |
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http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962016001100105 |
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