Aortic stenosis with abnormal eccentric left ventricular remodeling secondary to hypothyroidism in a Bourdeaux Mastiff

ABSTRACT: This paper describes a case of congenital aortic stenosis with eccentric left ventricular hypertrophy associated with hypothyroidism in a 1-year-old Bourdeaux Mastiff dog. The dog had ascites, apathy, alopecic and erythematous skin lesions in different parts of the body. A two-dimensional echocardiogram revealed aortic valve stenosis, with poststenotic dilation in the ascending aorta. The same exam showed eccentric hypertrophy and dilation of the left ventricle during systole and diastole. Aortic stenosis usually results in concentric left ventricular hypertrophy instead of eccentric hypertrophy; and therefore, this finding was very unusual. Hypothyroidism, which is uncommon in young dogs, may be incriminated as the cause of ventricular dilation, making this report even more interesting. Because hypothyroidism would only result in dilatation, the eccentric hypertrophy was attributed to pressure overload caused by aortic stenosis. Thus, cardiac alterations of this case represent a paradoxical association of both diseases.

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Main Authors: Minozzo,Guilherme Augusto, Stedile,Simone Tostes de Oliveira, Sousa,Marlos Gonçalves
Format: Digital revista
Language:English
Published: Universidade Federal de Santa Maria 2017
Online Access:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782017000900602
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spelling oai:scielo:S0103-847820170009006022017-07-26Aortic stenosis with abnormal eccentric left ventricular remodeling secondary to hypothyroidism in a Bourdeaux MastiffMinozzo,Guilherme AugustoStedile,Simone Tostes de OliveiraSousa,Marlos Gonçalves hypothyroidism echocardiogram ascending aorta left ventricular dilation heart disease ABSTRACT: This paper describes a case of congenital aortic stenosis with eccentric left ventricular hypertrophy associated with hypothyroidism in a 1-year-old Bourdeaux Mastiff dog. The dog had ascites, apathy, alopecic and erythematous skin lesions in different parts of the body. A two-dimensional echocardiogram revealed aortic valve stenosis, with poststenotic dilation in the ascending aorta. The same exam showed eccentric hypertrophy and dilation of the left ventricle during systole and diastole. Aortic stenosis usually results in concentric left ventricular hypertrophy instead of eccentric hypertrophy; and therefore, this finding was very unusual. Hypothyroidism, which is uncommon in young dogs, may be incriminated as the cause of ventricular dilation, making this report even more interesting. Because hypothyroidism would only result in dilatation, the eccentric hypertrophy was attributed to pressure overload caused by aortic stenosis. Thus, cardiac alterations of this case represent a paradoxical association of both diseases.info:eu-repo/semantics/openAccessUniversidade Federal de Santa MariaCiência Rural v.47 n.9 20172017-01-01info:eu-repo/semantics/articletext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782017000900602en10.1590/0103-8478cr20160424
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countrycode BR
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libraryname SciELO
language English
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author Minozzo,Guilherme Augusto
Stedile,Simone Tostes de Oliveira
Sousa,Marlos Gonçalves
spellingShingle Minozzo,Guilherme Augusto
Stedile,Simone Tostes de Oliveira
Sousa,Marlos Gonçalves
Aortic stenosis with abnormal eccentric left ventricular remodeling secondary to hypothyroidism in a Bourdeaux Mastiff
author_facet Minozzo,Guilherme Augusto
Stedile,Simone Tostes de Oliveira
Sousa,Marlos Gonçalves
author_sort Minozzo,Guilherme Augusto
title Aortic stenosis with abnormal eccentric left ventricular remodeling secondary to hypothyroidism in a Bourdeaux Mastiff
title_short Aortic stenosis with abnormal eccentric left ventricular remodeling secondary to hypothyroidism in a Bourdeaux Mastiff
title_full Aortic stenosis with abnormal eccentric left ventricular remodeling secondary to hypothyroidism in a Bourdeaux Mastiff
title_fullStr Aortic stenosis with abnormal eccentric left ventricular remodeling secondary to hypothyroidism in a Bourdeaux Mastiff
title_full_unstemmed Aortic stenosis with abnormal eccentric left ventricular remodeling secondary to hypothyroidism in a Bourdeaux Mastiff
title_sort aortic stenosis with abnormal eccentric left ventricular remodeling secondary to hypothyroidism in a bourdeaux mastiff
description ABSTRACT: This paper describes a case of congenital aortic stenosis with eccentric left ventricular hypertrophy associated with hypothyroidism in a 1-year-old Bourdeaux Mastiff dog. The dog had ascites, apathy, alopecic and erythematous skin lesions in different parts of the body. A two-dimensional echocardiogram revealed aortic valve stenosis, with poststenotic dilation in the ascending aorta. The same exam showed eccentric hypertrophy and dilation of the left ventricle during systole and diastole. Aortic stenosis usually results in concentric left ventricular hypertrophy instead of eccentric hypertrophy; and therefore, this finding was very unusual. Hypothyroidism, which is uncommon in young dogs, may be incriminated as the cause of ventricular dilation, making this report even more interesting. Because hypothyroidism would only result in dilatation, the eccentric hypertrophy was attributed to pressure overload caused by aortic stenosis. Thus, cardiac alterations of this case represent a paradoxical association of both diseases.
publisher Universidade Federal de Santa Maria
publishDate 2017
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782017000900602
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AT stedilesimonetostesdeoliveira aorticstenosiswithabnormaleccentricleftventricularremodelingsecondarytohypothyroidisminabourdeauxmastiff
AT sousamarlosgoncalves aorticstenosiswithabnormaleccentricleftventricularremodelingsecondarytohypothyroidisminabourdeauxmastiff
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