New phenolic glycosides from Phyllanthus cochinchinensis

New phenolic glycosides from Phyllanthus cochinchinensis

Chemical investigation of the whole plants of Phyllanthus cochinchinensis (Euphorbiaceae) led to the isolation of three new phenolic glycosides, phyllanthuosides A-C, together with 12 known compounds. Their structures were established on the basis of extensive spectroscopic analysis and chemical methods. Among them, phyllanthuosides A and B are two of the rare phenolic glycosides, featuring with a C6-C3-C6 skeleton. The absolute configurations of phyllanthuosides A and B were established by calculated electric circular dichroism (ECD) using time dependent density functional theory (TDDFT). The isolates were also tested for their cytotoxicity and antimicrobial activity.

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Main Authors: Zhao,Jian-Qiang, Wang,Yan-Ming, Lv,Jun-Jiang, Zhu,Hong-Tao, Wang,Dong, Yang,Chong-Ren, Xu,Min, Zhang,Ying-Jun
Format: Digital revista
Language:English
Published: Sociedade Brasileira de Química 2014
Online Access:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532014000800016
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spelling oai:scielo:S0103-505320140008000162014-08-04New phenolic glycosides from Phyllanthus cochinchinensisZhao,Jian-QiangWang,Yan-MingLv,Jun-JiangZhu,Hong-TaoWang,DongYang,Chong-RenXu,MinZhang,Ying-Jun Phyllantus cochinchinensis Euphorbiaceae phenolic glycosides cytotoxicity antimicrobial activity Chemical investigation of the whole plants of Phyllanthus cochinchinensis (Euphorbiaceae) led to the isolation of three new phenolic glycosides, phyllanthuosides A-C, together with 12 known compounds. Their structures were established on the basis of extensive spectroscopic analysis and chemical methods. Among them, phyllanthuosides A and B are two of the rare phenolic glycosides, featuring with a C6-C3-C6 skeleton. The absolute configurations of phyllanthuosides A and B were established by calculated electric circular dichroism (ECD) using time dependent density functional theory (TDDFT). The isolates were also tested for their cytotoxicity and antimicrobial activity.info:eu-repo/semantics/openAccessSociedade Brasileira de QuímicaJournal of the Brazilian Chemical Society v.25 n.8 20142014-08-01info:eu-repo/semantics/articletext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532014000800016en10.5935/0103-5053.20140127
institution SCIELO
collection OJS
country Brasil
countrycode BR
component Revista
access En linea
databasecode rev-scielo-br
tag revista
region America del Sur
libraryname SciELO
language English
format Digital
author Zhao,Jian-Qiang
Wang,Yan-Ming
Lv,Jun-Jiang
Zhu,Hong-Tao
Wang,Dong
Yang,Chong-Ren
Xu,Min
Zhang,Ying-Jun
spellingShingle Zhao,Jian-Qiang
Wang,Yan-Ming
Lv,Jun-Jiang
Zhu,Hong-Tao
Wang,Dong
Yang,Chong-Ren
Xu,Min
Zhang,Ying-Jun
New phenolic glycosides from Phyllanthus cochinchinensis
author_facet Zhao,Jian-Qiang
Wang,Yan-Ming
Lv,Jun-Jiang
Zhu,Hong-Tao
Wang,Dong
Yang,Chong-Ren
Xu,Min
Zhang,Ying-Jun
author_sort Zhao,Jian-Qiang
title New phenolic glycosides from Phyllanthus cochinchinensis
title_short New phenolic glycosides from Phyllanthus cochinchinensis
title_full New phenolic glycosides from Phyllanthus cochinchinensis
title_fullStr New phenolic glycosides from Phyllanthus cochinchinensis
title_full_unstemmed New phenolic glycosides from Phyllanthus cochinchinensis
title_sort new phenolic glycosides from phyllanthus cochinchinensis
description Chemical investigation of the whole plants of Phyllanthus cochinchinensis (Euphorbiaceae) led to the isolation of three new phenolic glycosides, phyllanthuosides A-C, together with 12 known compounds. Their structures were established on the basis of extensive spectroscopic analysis and chemical methods. Among them, phyllanthuosides A and B are two of the rare phenolic glycosides, featuring with a C6-C3-C6 skeleton. The absolute configurations of phyllanthuosides A and B were established by calculated electric circular dichroism (ECD) using time dependent density functional theory (TDDFT). The isolates were also tested for their cytotoxicity and antimicrobial activity.
publisher Sociedade Brasileira de Química
publishDate 2014
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532014000800016
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