Effects of a continuous rate infusion of butorphanol in isoflurane-anesthetized horses on cardiorespiratory parameters, recovery quality, gastrointestinal motility and serum cortisol concentrations
PURPOSE: To assess the cardiorespiratory parametes, recovery, gastrointestinal motility and serum cortisol concentrations in horses anesthetized with isoflurane with or without a continuous rate infusion (CRI) of butorphanol for orchiectomy. METHODS: Twelve adult, intact, male horses weighing 332 ± 55 kg were included in the study. Xilazine was administered as premedication. Anesthesia was induced with ketamine and midazolam and maintained with isoflurane. Butorphanol (0.025 mg kg-1 bolus) or an equivalent volume of saline (0.9%) was given intravenously followed by a CRI of butorphanol (BG) (13 µg kg-1 hour-1) or saline (CG). Cardiorespiratory variables were recorded before (T0) and every 15 minutes for 75 minutes after the start of infusion. Serum cortisol concentration was measured at T0 and 60 minutes, and 30 minutes and 19 hours after the horse stood up. Recovery from anesthesia was evaluated using a scoring system. Gastrointestinal motility was evaluated before anesthesia and during 24 hours after recovery. RESULTS: There were no significant differences between groups in cardiopulmonary variables, or recovery scores or serum cortisol concentrations. A reduction in gastrointestinal motility was recorded for 60 minutes in BG. CONCLUSIONS: Continuous rate infusion of butorphanol in horses anesthetized with isoflurane did not adversely affect the cardiopulmonary variables monitored, or recovery scores. A small but statistically significant reduction in gastrointestinal motility occurred in the butorphanol group.
Main Authors: | , , , , , , , |
---|---|
Format: | Digital revista |
Language: | English |
Published: |
Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia
2014
|
Online Access: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-86502014001200801 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
id |
oai:scielo:S0102-86502014001200801 |
---|---|
record_format |
ojs |
spelling |
oai:scielo:S0102-865020140012008012015-07-30Effects of a continuous rate infusion of butorphanol in isoflurane-anesthetized horses on cardiorespiratory parameters, recovery quality, gastrointestinal motility and serum cortisol concentrationsDias,Bianca PaludetoAraújo,Marcelo Augusto deDeschk,MaurícioTrein,Thomas AlexanderPinheiro,Nirmem CarlosPerri,Silvia Helena VenturolliRodrigues,Celso AntônioSantos,Paulo Sergio Patto dos Blood Gas Analysis Analgesics, Opioid Anesthesia, Inhalation Orchiectomy Horses PURPOSE: To assess the cardiorespiratory parametes, recovery, gastrointestinal motility and serum cortisol concentrations in horses anesthetized with isoflurane with or without a continuous rate infusion (CRI) of butorphanol for orchiectomy. METHODS: Twelve adult, intact, male horses weighing 332 ± 55 kg were included in the study. Xilazine was administered as premedication. Anesthesia was induced with ketamine and midazolam and maintained with isoflurane. Butorphanol (0.025 mg kg-1 bolus) or an equivalent volume of saline (0.9%) was given intravenously followed by a CRI of butorphanol (BG) (13 µg kg-1 hour-1) or saline (CG). Cardiorespiratory variables were recorded before (T0) and every 15 minutes for 75 minutes after the start of infusion. Serum cortisol concentration was measured at T0 and 60 minutes, and 30 minutes and 19 hours after the horse stood up. Recovery from anesthesia was evaluated using a scoring system. Gastrointestinal motility was evaluated before anesthesia and during 24 hours after recovery. RESULTS: There were no significant differences between groups in cardiopulmonary variables, or recovery scores or serum cortisol concentrations. A reduction in gastrointestinal motility was recorded for 60 minutes in BG. CONCLUSIONS: Continuous rate infusion of butorphanol in horses anesthetized with isoflurane did not adversely affect the cardiopulmonary variables monitored, or recovery scores. A small but statistically significant reduction in gastrointestinal motility occurred in the butorphanol group. info:eu-repo/semantics/openAccessSociedade Brasileira para o Desenvolvimento da Pesquisa em CirurgiaActa Cirúrgica Brasileira v.29 n.12 20142014-12-01info:eu-repo/semantics/articletext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-86502014001200801en10.1590/S0102-86502014001900006 |
institution |
SCIELO |
collection |
OJS |
country |
Brasil |
countrycode |
BR |
component |
Revista |
access |
En linea |
databasecode |
rev-scielo-br |
tag |
revista |
region |
America del Sur |
libraryname |
SciELO |
language |
English |
format |
Digital |
author |
Dias,Bianca Paludeto Araújo,Marcelo Augusto de Deschk,Maurício Trein,Thomas Alexander Pinheiro,Nirmem Carlos Perri,Silvia Helena Venturolli Rodrigues,Celso Antônio Santos,Paulo Sergio Patto dos |
spellingShingle |
Dias,Bianca Paludeto Araújo,Marcelo Augusto de Deschk,Maurício Trein,Thomas Alexander Pinheiro,Nirmem Carlos Perri,Silvia Helena Venturolli Rodrigues,Celso Antônio Santos,Paulo Sergio Patto dos Effects of a continuous rate infusion of butorphanol in isoflurane-anesthetized horses on cardiorespiratory parameters, recovery quality, gastrointestinal motility and serum cortisol concentrations |
author_facet |
Dias,Bianca Paludeto Araújo,Marcelo Augusto de Deschk,Maurício Trein,Thomas Alexander Pinheiro,Nirmem Carlos Perri,Silvia Helena Venturolli Rodrigues,Celso Antônio Santos,Paulo Sergio Patto dos |
author_sort |
Dias,Bianca Paludeto |
title |
Effects of a continuous rate infusion of butorphanol in isoflurane-anesthetized horses on cardiorespiratory parameters, recovery quality, gastrointestinal motility and serum cortisol concentrations |
title_short |
Effects of a continuous rate infusion of butorphanol in isoflurane-anesthetized horses on cardiorespiratory parameters, recovery quality, gastrointestinal motility and serum cortisol concentrations |
title_full |
Effects of a continuous rate infusion of butorphanol in isoflurane-anesthetized horses on cardiorespiratory parameters, recovery quality, gastrointestinal motility and serum cortisol concentrations |
title_fullStr |
Effects of a continuous rate infusion of butorphanol in isoflurane-anesthetized horses on cardiorespiratory parameters, recovery quality, gastrointestinal motility and serum cortisol concentrations |
title_full_unstemmed |
Effects of a continuous rate infusion of butorphanol in isoflurane-anesthetized horses on cardiorespiratory parameters, recovery quality, gastrointestinal motility and serum cortisol concentrations |
title_sort |
effects of a continuous rate infusion of butorphanol in isoflurane-anesthetized horses on cardiorespiratory parameters, recovery quality, gastrointestinal motility and serum cortisol concentrations |
description |
PURPOSE: To assess the cardiorespiratory parametes, recovery, gastrointestinal motility and serum cortisol concentrations in horses anesthetized with isoflurane with or without a continuous rate infusion (CRI) of butorphanol for orchiectomy. METHODS: Twelve adult, intact, male horses weighing 332 ± 55 kg were included in the study. Xilazine was administered as premedication. Anesthesia was induced with ketamine and midazolam and maintained with isoflurane. Butorphanol (0.025 mg kg-1 bolus) or an equivalent volume of saline (0.9%) was given intravenously followed by a CRI of butorphanol (BG) (13 µg kg-1 hour-1) or saline (CG). Cardiorespiratory variables were recorded before (T0) and every 15 minutes for 75 minutes after the start of infusion. Serum cortisol concentration was measured at T0 and 60 minutes, and 30 minutes and 19 hours after the horse stood up. Recovery from anesthesia was evaluated using a scoring system. Gastrointestinal motility was evaluated before anesthesia and during 24 hours after recovery. RESULTS: There were no significant differences between groups in cardiopulmonary variables, or recovery scores or serum cortisol concentrations. A reduction in gastrointestinal motility was recorded for 60 minutes in BG. CONCLUSIONS: Continuous rate infusion of butorphanol in horses anesthetized with isoflurane did not adversely affect the cardiopulmonary variables monitored, or recovery scores. A small but statistically significant reduction in gastrointestinal motility occurred in the butorphanol group. |
publisher |
Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia |
publishDate |
2014 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-86502014001200801 |
work_keys_str_mv |
AT diasbiancapaludeto effectsofacontinuousrateinfusionofbutorphanolinisofluraneanesthetizedhorsesoncardiorespiratoryparametersrecoveryqualitygastrointestinalmotilityandserumcortisolconcentrations AT araujomarceloaugustode effectsofacontinuousrateinfusionofbutorphanolinisofluraneanesthetizedhorsesoncardiorespiratoryparametersrecoveryqualitygastrointestinalmotilityandserumcortisolconcentrations AT deschkmauricio effectsofacontinuousrateinfusionofbutorphanolinisofluraneanesthetizedhorsesoncardiorespiratoryparametersrecoveryqualitygastrointestinalmotilityandserumcortisolconcentrations AT treinthomasalexander effectsofacontinuousrateinfusionofbutorphanolinisofluraneanesthetizedhorsesoncardiorespiratoryparametersrecoveryqualitygastrointestinalmotilityandserumcortisolconcentrations AT pinheironirmemcarlos effectsofacontinuousrateinfusionofbutorphanolinisofluraneanesthetizedhorsesoncardiorespiratoryparametersrecoveryqualitygastrointestinalmotilityandserumcortisolconcentrations AT perrisilviahelenaventurolli effectsofacontinuousrateinfusionofbutorphanolinisofluraneanesthetizedhorsesoncardiorespiratoryparametersrecoveryqualitygastrointestinalmotilityandserumcortisolconcentrations AT rodriguescelsoantonio effectsofacontinuousrateinfusionofbutorphanolinisofluraneanesthetizedhorsesoncardiorespiratoryparametersrecoveryqualitygastrointestinalmotilityandserumcortisolconcentrations AT santospaulosergiopattodos effectsofacontinuousrateinfusionofbutorphanolinisofluraneanesthetizedhorsesoncardiorespiratoryparametersrecoveryqualitygastrointestinalmotilityandserumcortisolconcentrations |
_version_ |
1756400957795598336 |