Pulmonary Thromboendarterectomy Without Circulatory Arrest

Abstract Introduction: Here we describe our technique and results of beating heart pulmonary thromboendarterectomy (PTE) with cardiopulmonary bypass (CPB) in four patients for treatment of chronic thromboembolic pulmonary hypertension (CTEPH). Methods: Retrospective analysis of data from patients who underwent PTE for CTEPH between January 2019 and September 2020. Patients were followed up with clinical assessment, 2D echocardiography, and computed tomography pulmonary angiogram. Results: Four patients were operated for CTEPH using our technique. Moderate tricuspid regurgitation (TR) and severe TR were found in two patients each. Severe right ventricular (RV) dysfunction was found in all cases. Thrombi were classified as Jamieson type II in three cases and type I in one case. Postoperative median direct manometric pulmonary artery (PA) pressures decreased (from 46.5 mmHg to 23.5 mmHg), median CPB time was 126 minutes, and median temperature was 33.35 °C. Mechanical ventilation was for a median of 19.5 hours. There was one re-exploration. Median intensive care unit stay was 7.5 days. There was no mortality. Postoperative 2D echocardiography revealed decrease in median PA systolic pressures (from 85 mmHg to 33 mmHg), improvement in RV function by tricuspid annular plane systolic excursion (median 14 mm vs. 16 mm), and improved postoperative oxygen saturations (88.5% vs. 99%). In follow-up (ranging between 2-15 months), all patients reported improvement in quality of life and were in New York Heart Association class I. Conclusion: With our described simple modifications, advances in perfusion, and blood conservation technologies, one can avoid the need for deep hypothermic circulatory arrest during PTE.

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Main Authors: Kynta,Reuben Lamiaki, Rawat,Sanjib, Mandal,Mrinal, Saikia,Manuj Kumar
Format: Digital revista
Language:English
Published: Sociedade Brasileira de Cirurgia Cardiovascular 2022
Online Access:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-76382022000300394
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spelling oai:scielo:S0102-763820220003003942022-05-31Pulmonary Thromboendarterectomy Without Circulatory ArrestKynta,Reuben LamiakiRawat,SanjibMandal,MrinalSaikia,Manuj Kumar Pulmonary Hypertension Pulmonary Artery Endarterectomy Cardiopulmonary Bypass Temperature Oxygen Tricuspid Valve Insufficiency Quality of Life Abstract Introduction: Here we describe our technique and results of beating heart pulmonary thromboendarterectomy (PTE) with cardiopulmonary bypass (CPB) in four patients for treatment of chronic thromboembolic pulmonary hypertension (CTEPH). Methods: Retrospective analysis of data from patients who underwent PTE for CTEPH between January 2019 and September 2020. Patients were followed up with clinical assessment, 2D echocardiography, and computed tomography pulmonary angiogram. Results: Four patients were operated for CTEPH using our technique. Moderate tricuspid regurgitation (TR) and severe TR were found in two patients each. Severe right ventricular (RV) dysfunction was found in all cases. Thrombi were classified as Jamieson type II in three cases and type I in one case. Postoperative median direct manometric pulmonary artery (PA) pressures decreased (from 46.5 mmHg to 23.5 mmHg), median CPB time was 126 minutes, and median temperature was 33.35 °C. Mechanical ventilation was for a median of 19.5 hours. There was one re-exploration. Median intensive care unit stay was 7.5 days. There was no mortality. Postoperative 2D echocardiography revealed decrease in median PA systolic pressures (from 85 mmHg to 33 mmHg), improvement in RV function by tricuspid annular plane systolic excursion (median 14 mm vs. 16 mm), and improved postoperative oxygen saturations (88.5% vs. 99%). In follow-up (ranging between 2-15 months), all patients reported improvement in quality of life and were in New York Heart Association class I. Conclusion: With our described simple modifications, advances in perfusion, and blood conservation technologies, one can avoid the need for deep hypothermic circulatory arrest during PTE.info:eu-repo/semantics/openAccessSociedade Brasileira de Cirurgia CardiovascularBrazilian Journal of Cardiovascular Surgery v.37 n.3 20222022-06-01info:eu-repo/semantics/articletext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-76382022000300394en10.21470/1678-9741-2020-0534
institution SCIELO
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country Brasil
countrycode BR
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databasecode rev-scielo-br
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region America del Sur
libraryname SciELO
language English
format Digital
author Kynta,Reuben Lamiaki
Rawat,Sanjib
Mandal,Mrinal
Saikia,Manuj Kumar
spellingShingle Kynta,Reuben Lamiaki
Rawat,Sanjib
Mandal,Mrinal
Saikia,Manuj Kumar
Pulmonary Thromboendarterectomy Without Circulatory Arrest
author_facet Kynta,Reuben Lamiaki
Rawat,Sanjib
Mandal,Mrinal
Saikia,Manuj Kumar
author_sort Kynta,Reuben Lamiaki
title Pulmonary Thromboendarterectomy Without Circulatory Arrest
title_short Pulmonary Thromboendarterectomy Without Circulatory Arrest
title_full Pulmonary Thromboendarterectomy Without Circulatory Arrest
title_fullStr Pulmonary Thromboendarterectomy Without Circulatory Arrest
title_full_unstemmed Pulmonary Thromboendarterectomy Without Circulatory Arrest
title_sort pulmonary thromboendarterectomy without circulatory arrest
description Abstract Introduction: Here we describe our technique and results of beating heart pulmonary thromboendarterectomy (PTE) with cardiopulmonary bypass (CPB) in four patients for treatment of chronic thromboembolic pulmonary hypertension (CTEPH). Methods: Retrospective analysis of data from patients who underwent PTE for CTEPH between January 2019 and September 2020. Patients were followed up with clinical assessment, 2D echocardiography, and computed tomography pulmonary angiogram. Results: Four patients were operated for CTEPH using our technique. Moderate tricuspid regurgitation (TR) and severe TR were found in two patients each. Severe right ventricular (RV) dysfunction was found in all cases. Thrombi were classified as Jamieson type II in three cases and type I in one case. Postoperative median direct manometric pulmonary artery (PA) pressures decreased (from 46.5 mmHg to 23.5 mmHg), median CPB time was 126 minutes, and median temperature was 33.35 °C. Mechanical ventilation was for a median of 19.5 hours. There was one re-exploration. Median intensive care unit stay was 7.5 days. There was no mortality. Postoperative 2D echocardiography revealed decrease in median PA systolic pressures (from 85 mmHg to 33 mmHg), improvement in RV function by tricuspid annular plane systolic excursion (median 14 mm vs. 16 mm), and improved postoperative oxygen saturations (88.5% vs. 99%). In follow-up (ranging between 2-15 months), all patients reported improvement in quality of life and were in New York Heart Association class I. Conclusion: With our described simple modifications, advances in perfusion, and blood conservation technologies, one can avoid the need for deep hypothermic circulatory arrest during PTE.
publisher Sociedade Brasileira de Cirurgia Cardiovascular
publishDate 2022
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-76382022000300394
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AT mandalmrinal pulmonarythromboendarterectomywithoutcirculatoryarrest
AT saikiamanujkumar pulmonarythromboendarterectomywithoutcirculatoryarrest
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